Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GLB1 | P16278 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17506636 | 0.87 | PTPN7 (0.36) | GBA1SMN1; SMN2ALOX5 | |
| SCHEMBL17506616 | 0.85 | ARG1 (0.34) | — | |
| SCHEMBL17506694 | 0.85 | ARG1 (0.39) | — | |
| SCHEMBL17506629 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2 | |
| SCHEMBL20331801 | 0.82 | ARG1 (0.44) | GBA1 | |
| SCHEMBL21902870 | 0.82 | CYP1A2 (0.39) | SMN1; SMN2 | |
| SCHEMBL17506559 | 0.81 | ARG1 (0.34) | — | |
| SCHEMBL17506575 | 0.77 | ARG1 (0.44) | — | |
| SCHEMBL17506595 | 0.76 | ARG1 (0.43) | — | |
| SCHEMBL24248171 | 0.76 | CHRNB2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3034509-A1 | ARGINASE INHIBITORS AS THERAPEUTICS | Mars, Incorporated (US) | 2016-06-22 | — | — | EP | disclosed |