Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 17/20 | 0.37 |
| ▸ | IMPDH1 | P20839 | 6/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17491545 | 0.79 | GAA (0.39) | IMPDH2IMPDH1 | |
| SCHEMBL17491493 | 0.79 | IMPDH2 (0.40) | IMPDH2IMPDH1 | |
| SCHEMBL17491487 | 0.78 | DYRK1A (0.44) | CYP1A2 | |
| SCHEMBL17491553 | 0.78 | SGK1 (0.33) | PDE4B | |
| SCHEMBL17491406 | 0.75 | MAOA (0.40) | IMPDH2PDE4BCYP1A2 | |
| SCHEMBL17491492 | 0.73 | ROCK2 (0.46) | IMPDH2 | |
| SCHEMBL17491433 | 0.73 | CYP3A4 (0.47) | PDE4B | |
| SCHEMBL17491444 | 0.69 | IMPDH2 (0.39) | IMPDH2 | |
| SCHEMBL28710975 | 0.67 | IMPDH2 (0.47) | IMPDH2IMPDH1 | |
| SCHEMBL22188032 | 0.64 | IMPDH2 (0.60) | IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982670-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2016-02-10 | — | — | EP | disclosed |