Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.65 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.65 |
| ▸ | TUBB | P07437 | 5/20 | 0.65 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.65 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.65 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.65 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.65 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.65 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.65 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.65 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.65 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.65 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.65 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.65 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17507466 | 0.89 | TUBB1 (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29236859 | 0.87 | LMNA (0.64) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30969381 | 0.87 | LMNA (0.64) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12435907 | 0.87 | TUBB4A (0.49) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29236861 | 0.84 | LMNA (0.54) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30969396 | 0.83 | HTT (0.56) | TUBB1LMNAHTTALDH1A1NPC1 | |
| SCHEMBL29236666 | 0.83 | HTT (0.56) | TUBB1LMNAHTTALDH1A1NPC1 | |
| SCHEMBL30504089 | 0.81 | SLC22A6 (0.57) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29236683 | 0.81 | LMNA (0.56) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29236694 | 0.81 | NPC1 (0.73) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688637-B2 | 3-amidobenzamides and uses thereof for increasing cellular levels of A3G and other A3 family members | NORTHWESTERN UNIVERSTIY (US) | 2017-06-27 | — | — | US | disclosed |
| EP-2351731-B1 | A GROUP OF AMINO SUBSTITUTED BENZOYL DERIVATIVES AND THEIR PREPARATION AND THEIR USE | INST MED BIOTECHNOLOGY CAMS (CN) | 2016-02-10 | — | — | EP | disclosed |