Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662203 | 0.86 | PTPN7 (0.47) | KIF11NR3C2ARPTPN7DUSP3 | |
| SCHEMBL17508193 | 0.82 | RAB9A (0.56) | KIF11ARPTPN7DUSP3 | |
| SCHEMBL67628 | 0.82 | KIF11 (0.58) | KIF11AR | |
| SCHEMBL10299815 | 0.82 | KIF11 (0.58) | KIF11AR | |
| SCHEMBL9901133 | 0.82 | IDO1 (0.51) | KIF11P2RX7 | |
| SCHEMBL17508169 | 0.80 | CYP17A1 (0.44) | KIF11KMT2A | |
| SCHEMBL30679640 | 0.79 | KIF11 (0.75) | KIF11AR | |
| SCHEMBL30486158 | 0.79 | PTPN7 (0.47) | KIF11NR3C2ARPTPN7DUSP3 | |
| SCHEMBL250310 | 0.79 | PTPN7 (0.47) | KIF11NR3C2ARPTPN7DUSP3 | |
| SCHEMBL1283899 | 0.75 | KIF11 (0.51) | KIF11ARL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016019588-A1 | OXACAZONE COMPOUNDS TO TREAT CLOSTRIDIUM DIFFICILE | THE BROAD INSTITUTE, INC. (US) | 2016-02-11 | — | — | WO | disclosed |
| WO-2016019588-A1 | OXACAZONE COMPOUNDS TO TREAT CLOSTRIDIUM DIFFICILE | THE BROAD INSTITUTE, INC. (US) | 2016-02-11 | — | — | WO | disclosed |