Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29771432 | 0.92 | L3MBTL1 (0.41) | L3MBTL1KDRKCNN4HPGDMAPK1 | |
| SCHEMBL70574 | 0.88 | L3MBTL1 (0.44) | L3MBTL1KDRKCNN4ALDH1A1HPGD | |
| SCHEMBL9058051 | 0.84 | SLC2A1 (0.39) | ALDH1A3LMNAL3MBTL1FLT3KDR | |
| SCHEMBL22614609 | 0.81 | SCN5A (0.44) | KCNH2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL8814676 | 0.80 | L3MBTL1 (0.40) | KCNH2L3MBTL1KDRKCNN4ALDH1A1 | |
| SCHEMBL3847041 | 0.79 | MEN1 (0.46) | LMNAKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL3846776 | 0.79 | ATM (0.41) | NR3C1PGRALDH1A1HPGDMAPK1 | |
| SCHEMBL8320062 | 0.78 | AXL (0.54) | — | |
| SCHEMBL27869499 | 0.76 | L3MBTL1 (0.52) | LMNAL3MBTL1GPR55KDRKDM4E | |
| SCHEMBL29771434 | 0.75 | CREBBP (0.35) | GRM5LMNAKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968579-B2 | Antifungal triazole derivatives | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2011-06-28 | — | — | US | disclosed |
| CN-101365692-A | Novel antifungal triazole derivatives | DAE WOONG PHARMA (KR) | 2009-02-11 | — | — | CN | disclosed |
| US-20080287440-A1 | Novel Antifungal Triazole Derivatives | DAEWOONG PHARMACEUTIDCAL CO., LTD. (KR) | 2008-11-20 | — | — | US | disclosed |
| EP-1951705-A1 | NOVEL ANTIFUNGAL TRIAZOLE DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007052943-A1 | NOVEL ANTIFUNGAL TRIAZOLE DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2007-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287440-A1 | Novel Antifungal Triazole Derivatives | CYP51A1, ERG28, CYP3A43 | NR3C1 1012/4885ALDH1A3 2611/4885MLNR 2948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.