SCHEMBL17508266

SCHEMBL17508266

Cc1cccc(Cc2ccccc2C=O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
ALDH1A1 P00352 1/20 0.46
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
DAO P14920 1/20 0.42
TBXA2R P21731 3/20 0.41
PTGER3 P43115 3/20 0.41
PTGER2 P43116 3/20 0.41
PTGDR Q13258 3/20 0.41
PTGER4 P35408 2/20 0.41
PTGFR P43088 2/20 0.41
TAAR1 Q96RJ0 1/20 0.41
PTGER1 P34995 1/20 0.40
PTGIR P43119 1/20 0.40
IDO1 P14902 1/20 0.40
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
MPO P05164 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10727696 0.82 ALDH1A1 (0.52) TSHRALDH1A1MAOAMAOBTBXA2R
SCHEMBL31588310 0.82 LMNA (0.52) TSHRALDH1A1TBXA2RPTGER3PTGER2
SCHEMBL872046 0.82 LMNA (0.52) TSHRALDH1A1TBXA2RPTGER3PTGER2
SCHEMBL28319707 0.81 ALDH1A1 (0.55) TSHRALDH1A1TBXA2RPTGER3PTGER2
SCHEMBL8096568 0.80 DAO (0.47) TSHRDAOTAAR1IDO1CYP3A4
SCHEMBL17508277 0.80 ALDH1A1 (0.49) ALDH1A1MAOAMAOBDAOTAAR1
SCHEMBL20767534 0.80 MEN1 (0.44) ALDH1A1MAOAMAOBDAOTBXA2R
SCHEMBL2474493 0.80 MEN1 (0.49) ALDH1A1TAAR1IDO1MEN1LMNA
SCHEMBL8096061 0.79 LTA4H (0.46) TSHRDAOTAAR1IDO1CYP3A4
SCHEMBL31236994 0.79 SRC (0.47) TSHRALDH1A1CYP3A4CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111233599-B Aromatic ring ortho-iodoalkanone and synthetic method and application thereof 兰州大学 2021-07-20 CN disclosed
CN-111233599-A Aromatic ring ortho-iodoalkanone and synthetic method and application thereof 兰州大学 2020-06-05 CN disclosed
WO-2016019588-A1 OXACAZONE COMPOUNDS TO TREAT CLOSTRIDIUM DIFFICILE THE BROAD INSTITUTE, INC. (US) 2016-02-11 WO disclosed