Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 16/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17510093 | 0.91 | MAPK1 (0.40) | S1PR1ALOX5S1PR4S1PR5HTR2C | |
| SCHEMBL2327510 | 0.91 | S1PR1 (0.43) | S1PR1ALOX5S1PR4S1PR5SLC6A5 | |
| Hydrochloric Acid SCHEMBL17530055 | 0.90 | S1PR1 (0.43) | S1PR1ALOX5S1PR4S1PR5SLC6A5 | |
| SCHEMBL10088987 | 0.86 | ALDH1A1 (0.46) | — | |
| SCHEMBL2327269 | 0.86 | S1PR1 (0.45) | S1PR1S1PR4S1PR5S1PR3 | |
| SCHEMBL10088834 | 0.84 | ENPP2 (0.44) | S1PR1ALOX5S1PR4S1PR5S1PR3 | |
| SCHEMBL10088838 | 0.84 | S1PR1 (0.43) | S1PR1ALOX5S1PR4S1PR5S1PR3 | |
| SCHEMBL10089046 | 0.83 | ALOX5 (0.38) | S1PR1ALOX5S1PR4S1PR5 | |
| SCHEMBL10089073 | 0.83 | ALOX5 (0.38) | S1PR1ALOX5S1PR4S1PR5 | |
| SCHEMBL10088832 | 0.82 | S1PR1 (0.43) | S1PR1ALOX5S1PR4S1PR5S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2354134-B1 | 2H-CHROMENE DERIVATIVES AS STIMULATORS OF SPHINGOSINE 1-PHOSPHATE RECEPTOR | ASTELLAS PHARMA INC (JP) | 2016-02-24 | — | — | EP | claimed |