Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 2/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29663619 | 0.85 | FABP5 (0.44) | FABP7FABP5KMT2AP2RX7EPHX2 | |
| SCHEMBL17513203 | 0.79 | FABP5 (0.39) | FABP7FABP5KMT2AP2RX7EPHX2 | |
| SCHEMBL17513345 | 0.74 | CASP3 (0.48) | FABP7FABP5KMT2AEPHX2TP53 | |
| SCHEMBL19378090 | 0.74 | CASP3 (0.48) | FABP7FABP5KMT2AEPHX2TP53 | |
| SCHEMBL16634841 | 0.71 | SMN1; SMN2 (0.46) | FABP7FABP5KMT2AEPHX2CYP1A2 | |
| SCHEMBL29928500 | 0.71 | MDM4 (0.51) | KMT2AEPHX2TP53 | |
| SCHEMBL30532481 | 0.71 | MDM4 (0.51) | KMT2AEPHX2TP53 | |
| SCHEMBL29872206 | 0.71 | MDM4 (0.51) | KMT2AEPHX2TP53 | |
| SCHEMBL29907877 | 0.71 | MDM4 (0.51) | KMT2AEPHX2TP53 | |
| SCHEMBL120613 | 0.71 | MDM4 (0.51) | KMT2AEPHX2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029146-A1 | SPECIFIC INHIBITORS OF METHIONYL-TRNA SYNTHETASE | UNIVERSITY OF WASHINGTON (US) | 2016-02-25 | — | — | WO | claimed |