Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 2/20 | 0.46 |
| ▸ | PLG | P00747 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 2/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28607801 | 0.83 | KMT2A (0.60) | PLA2G4APLGPLAURAPGEF4PPARG | |
| SCHEMBL1664063 | 0.81 | PLG (0.51) | PLA2G4APLGPLAURAPGEF4PPARG | |
| SCHEMBL5068315 | 0.81 | TUBB4A (0.57) | PLA2G4APLGPLAURAPGEF4PPARG | |
| SCHEMBL4934703 | 0.80 | PLA2G4A (0.55) | PLA2G4APLGPLAURAPGEF4PPARA | |
| SCHEMBL2983210 | 0.80 | PLA2G4A (0.48) | PLA2G4APLGPLAURAPGEF4PPARG | |
| SCHEMBL5387474 | 0.80 | TUBB4A (0.59) | PLA2G4APLGPLAURAPGEF4PPARG | |
| SCHEMBL4813289 | 0.78 | PLG (0.55) | PLA2G4APLGPLAUPPARGPPARD | |
| SCHEMBL1749895 | 0.78 | PLA2G4A (0.59) | PLA2G4APLGPLAUPPARAMCL1 | |
| SCHEMBL15921713 | 0.77 | PLA2G4A (0.55) | PLA2G4APLGPLAURAPGEF4PPARG | |
| SCHEMBL6752488 | 0.77 | HTR2C (0.55) | PLA2G4APLGPLAURAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027285-A2 | BICYCLIC HETEROARYL AMIDES AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS | ALKEM LABORATORIES LTD. (IN) | 2016-02-25 | — | — | WO | disclosed |