SCHEMBL17514545

SCHEMBL17514545

C#CCOc1[c]cccc1-c1ccc(F)cc1Cl

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.36
MAOB P27338 5/20 0.34
MAPK14 Q16539 1/20 0.34
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP1B1 Q16678 1/20 0.33
PTGDR2 Q9Y5Y4 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
MAOA P21397 2/20 0.31
HTR1A P08908 1/20 0.31
HTR7 P34969 1/20 0.31
GRM5 P41594 1/20 0.31
LMNA P02545 1/20 0.30
NISCH Q9Y2I1 1/20 0.30
GRM2 Q14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17514811 0.90 MAOB (0.34) HSD11B1MAOBMAPK14CYP1A1CYP1A2
SCHEMBL17514508 0.87 MAOB (0.35) MAOBMAPK14CYP1A1CYP1A2CYP1B1
SCHEMBL17514739 0.87 HPGD (0.36) MAOBCYP1A2NPC1RAB9AMAOA
SCHEMBL17514656 0.85 MAOB (0.36) MAOBNPC1RAB9AMAOALMNA
SCHEMBL17514482 0.85 MAOB (0.34) MAOBCYP1A1CYP1A2CYP1B1
SCHEMBL17514718 0.85 MAOB (0.34) MAOBMAPK14CYP1A1CYP1A2CYP1B1
SCHEMBL17514623 0.84 MAOB (0.35) MAOBCYP1A1CYP1A2CYP1B1MAOA
SCHEMBL17514594 0.83 KMO (0.34) MAOBCYP1A1CYP1A2CYP1B1
SCHEMBL17514775 0.82 HPGD (0.35) HSD11B1MAOBGRM2
SCHEMBL17514816 0.82 CYP1A1 (0.35) MAOBCYP1A1CYP1A2CYP1B1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016026830-A1 NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-25 WO disclosed