Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17514945 | 0.89 | HPGD (0.36) | HPGDTSHRMAOBKMT2AHTR2C | |
| SCHEMBL17514656 | 0.87 | MAOB (0.36) | HPGDMAOBMAPTMAPK1NPC1 | |
| SCHEMBL17514545 | 0.87 | HSD11B1 (0.36) | MAOBNPC1RAB9ACYP1A2MAOA | |
| SCHEMBL17514775 | 0.87 | HPGD (0.35) | HPGDTSHRMAOBKMT2AHTR2C | |
| SCHEMBL17514786 | 0.85 | HPGD (0.36) | HPGDTSHRMAOBKMT2AHTR2C | |
| SCHEMBL17514688 | 0.82 | MAOB (0.43) | HPGDTSHRMAOBKMT2AKDM4E | |
| SCHEMBL17514927 | 0.81 | MAOB (0.39) | HPGDTSHRMAOBKMT2AKDM4E | |
| SCHEMBL17514876 | 0.80 | MAOB (0.33) | MAOBMAPK1HSD17B10LMNA | |
| SCHEMBL17514594 | 0.80 | KMO (0.34) | MAOBMAPK1HSD17B10CYP1A2 | |
| SCHEMBL16395362 | 0.79 | POLB (0.38) | HPGDTSHRMAOBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016026830-A1 | NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | WO | disclosed |