SCHEMBL17514775

SCHEMBL17514775

C#CCOc1[c]cccc1-c1ccc(Cl)cc1F

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
MAOB P27338 3/20 0.35
KMT2A Q03164 1/20 0.34
HSD11B1 P28845 1/20 0.33
HTR2C P28335 2/20 0.32
HTR2B P41595 2/20 0.32
HTR2A P28223 1/20 0.32
EGLN2 Q96KS0 1/20 0.32
GRM2 Q14416 4/20 0.31
EGFR P00533 1/20 0.30
KMO O15229 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17514786 0.91 HPGD (0.36) HPGDTSHRMAOBKMT2AHTR2C
SCHEMBL17514739 0.87 HPGD (0.36) HPGDTSHRMAOBKMT2AHTR2C
SCHEMBL17514508 0.87 MAOB (0.35) MAOB
SCHEMBL17514945 0.84 HPGD (0.36) HPGDTSHRMAOBKMT2AHTR2C
SCHEMBL17514537 0.84 MAOB (0.35) MAOB
SCHEMBL17514545 0.82 HSD11B1 (0.36) MAOBHSD11B1GRM2
SCHEMBL17514807 0.82 MAOB (0.30) MAOB
SCHEMBL17514623 0.82 MAOB (0.35) MAOB
SCHEMBL17514720 0.81 PTGS2 (0.38) MAOBEGFR
SCHEMBL17514594 0.80 KMO (0.34) MAOBKMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016026830-A1 NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-25 WO disclosed