Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31081342 | 0.81 | KDM5B (0.47) | NOX4MAPTLDHAPOLBKDM5A | |
| SCHEMBL7809115 | 0.81 | KDM5B (0.47) | NOX4MAPTLDHAPOLBKDM5A | |
| SCHEMBL5394842 | 0.73 | MAPT (0.52) | MEN1KMT2AKDM4ETHRBALDH1A1 | |
| SCHEMBL14994888 | 0.71 | HTR2C (0.35) | NOX4MEN1KMT2AADORA2BPBRM1 | |
| SCHEMBL23400749 | 0.70 | MEN1 (0.51) | MEN1KMT2AKDM4EGAATHRB | |
| SCHEMBL23402302 | 0.69 | LDHA (0.48) | NOX4KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL17290637 | 0.68 | RAB9A (0.49) | MEN1KMT2AKDM4EGAATHRB | |
| SCHEMBL23402953 | 0.67 | KDM4E (0.49) | NOX4MEN1KMT2AKDM4EGAA | |
| SCHEMBL761767 | 0.67 | MEN1 (0.41) | MEN1KMT2AKDM4EGAATHRB | |
| SCHEMBL7167710 | 0.66 | GRIN2D (0.34) | NOX4MEN1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611297-A1 | FUNGICIDAL PYRAZOLES | E.I. Du Pont De Nemours And Company (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012030922-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-08 | — | — | WO | disclosed |