SCHEMBL17514976

SCHEMBL17514976

Fc1c(Cl)cccc1COc1cc[c]cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.44
NR4A2 P43354 2/20 0.41
MAOB P27338 6/20 0.40
MAOA P21397 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SGMS2 Q8NHU3 1/20 0.38
MRGPRX4 Q96LA9 2/20 0.37
TLR8 Q9NR97 1/20 0.36
MAPT P10636 2/20 0.36
TP53 P04637 1/20 0.36
GAA P10253 1/20 0.36
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
RAD52 P43351 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL697645 0.83 IDO1 (0.53) NR4A2MAOBMAOASMN1; SMN2NPC1
SCHEMBL17514826 0.83 MAOB (0.49) MAOBSMN1; SMN2NPC1RAB9AIDO1
SCHEMBL920476 0.83 NR4A2 (0.57) PTPN1NR4A2MAOBMAOANPC1
SCHEMBL17514756 0.81 MAOB (0.46) NR4A2MAOBMAOASMN1; SMN2NPC1
SCHEMBL919805 0.78 ALKBH1 (0.46) MAOBMAPTGAAMEN1KMT2A
SCHEMBL3869191 0.78 SMN1; SMN2 (0.62) SMN1; SMN2RAB9AMEN1KMT2A
SCHEMBL17514795 0.77 SMN1; SMN2 (0.52) SMN1; SMN2RAB9AMAPTTP53GAA
SCHEMBL863430 0.76 MAOB (0.60) MAOBSMN1; SMN2NPC1RAB9AIDO1
SCHEMBL4638542 0.75 MAOB (0.51) PTPN1NR4A2MAOBNPC1RAB9A
SCHEMBL17514658 0.74 RAB9A (0.53) NR4A2MAOBRAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016026830-A1 NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-25 WO disclosed