Sugi Predict

Sugi Predict / Compounds / SCHEMBL920476

SCHEMBL920476

SCHEMBL920476

Clc1ccccc1COc1cc[c]cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR4A2 P43354 2/20 0.57
▸ MAOB P27338 3/20 0.55
▸ MAOA P21397 1/20 0.55
▸ IDO1 P14902 2/20 0.50
▸ MAPT P10636 2/20 0.49
▸ TP53 P04637 1/20 0.49
▸ GAA P10253 1/20 0.49
▸ NPC1 O15118 1/20 0.49
▸ RAB9A P51151 1/20 0.49
▸ MEN1 O00255 2/20 0.48
▸ KMT2A Q03164 2/20 0.48
▸ HTT P42858 1/20 0.48
▸ RAD52 P43351 1/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.48
▸ LMNA P02545 2/20 0.47
▸ POLB P06746 1/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ PTPN1 P18031 2/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7170719 0.86 NR4A2 (0.71) NR4A2MAOBMAOAIDO1MAPT
SCHEMBL697645 0.86 IDO1 (0.53) NR4A2MAOBMAOAIDO1MAPT
SCHEMBL9812484 0.84 NR4A2 (0.69) NR4A2MAOBMAOAIDO1MAPT
SCHEMBL17514976 0.83 PTPN1 (0.44) NR4A2MAOBMAOAIDO1MAPT
SCHEMBL5543732 0.82 TAAR1 (0.44) NR4A2MAOBMAOAIDO1MAPT
SCHEMBL919574 0.81 NR4A2 (0.49) NR4A2MAOBMAOAIDO1MAPT
SCHEMBL27629702 0.81 TAAR1 (0.43) NR4A2MAOBMAOAIDO1MAPT
SCHEMBL3618405 0.79 MAPT (0.70) NR4A2MAOBMAOAIDO1MAPT
SCHEMBL3869191 0.79 SMN1; SMN2 (0.62) RAB9AMEN1KMT2A
SCHEMBL696921 0.79 NR4A2 (0.59) NR4A2IDO1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2566477-B1 AMINO-QUINOLINES AS KINASE INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2015-09-02 — — EP claimed
US-20130053375-A1 AMINO-QUINOLINES AS KINASE INHIBITORS GLAXO GROUP LIMITED 2013-02-28 — — US claimed
CN-102503894-A 5-substituted methylene imidazolidine-2, 4-diketone derivative as well as pharmaceutical composition and application thereof UNIV TIANJIN MEDICAL 2012-06-20 — — CN claimed
EP-3277674-B1 TRIAZOL DERIVATIVES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2019-09-11 — — EP disclosed
US-20180339976-A1 NOVEL TRIAZOLE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-11-29 — — US disclosed
US-20160060222-A1 AMINO-QUINOLINES AS KINASE INHIBITORS GLAXOSMITHKLINE LLC 2016-03-03 — — US disclosed
WO-2016026830-A1 NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-25 — — WO disclosed
EP-2566477-B1 AMINO-QUINOLINES AS KINASE INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2015-09-02 — — EP disclosed
CN-102532162-B 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMA CO LTD 2015-05-27 — — CN disclosed
CN-102503894-B 5-substituted methylene imidazolidine-2, 4-diketone derivative as well as pharmaceutical composition and application thereof UNIV TIANJIN MEDICAL 2014-08-20 — — CN disclosed
CN-103554080-A 1,4-pentadiene-3-ketoxime ester compounds containing heterocyclic groups as well as preparation method and application thereof UNIV GUIZHOU 2014-02-05 — — CN disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 — — EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 — — US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 — — EP disclosed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 — — US disclosed
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-05-04 — — US disclosed
CN-1705670-A 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds OTSUKA PHARMA CO LTD (JP) 2005-12-07 — — CN disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 — — EP disclosed
US-4578107-A Herbicidal imidazolidine-2-one derivatives OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1986-03-25 — — US disclosed
US-4198205-A SULFONIC ACID-FREE DISPERSE DYES BASF AKTIENGESELLSCHAFT (DE) 1980-04-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180339976-A1 NOVEL TRIAZOLE DERIVATIVES ERG28, CYP51A1, SBK3 NR4A2 1505/4885MAOB 1989/4885MAOA 2196/4885
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles NR2C2, NR4A3, NR4A2 NR4A2 3/4885MAOB 2140/4885MAOA 2885/4885
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 NR4A2 573/4885MAOB 3730/4885MAOA 3447/4885
US-20160060222-A1 AMINO-QUINOLINES AS KINASE INHIBITORS ABL1, MAP3K2, MAP4K2 NR4A2 1498/4885MAOB 1961/4885MAOA 2332/4885
US-20130053375-A1 AMINO-QUINOLINES AS KINASE INHIBITORS ABL1, MAP3K2, MAP4K2 NR4A2 1498/4885MAOB 1961/4885MAOA 2332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.