SCHEMBL17514985

SCHEMBL17514985

COc1[c]cccc1-c1cc(F)cc(Cl)c1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 5/20 0.36
PGR P06401 3/20 0.32
MAP4K4 O95819 1/20 0.30
MET P08581 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6191314 0.89 ABL1 (0.33) CHRM3MET
SCHEMBL17514815 0.80 NOTUM (0.41)
SCHEMBL16719652 0.80 TUBB4A (0.40)
SCHEMBL17514938 0.79 PTGS2 (0.46) CHRM3
SCHEMBL17514964 0.79 MAOB (0.34) CHRM3
SCHEMBL17514584 0.78 TUBB4A (0.33)
SCHEMBL17514813 0.78 SLC6A4 (0.42)
SCHEMBL6985969 0.78 SLC6A4 (0.42)
SCHEMBL17514958 0.77 DPP4 (0.35)
SCHEMBL17514992 0.76 HSD11B1 (0.35) CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016026830-A1 NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-25 WO disclosed