SCHEMBL17515774

SCHEMBL17515774

COc1ccccc1N=Nc1ccc(N=Nc2c(S(=O)(=O)O)cc3cc(Nc4ccccc4)ccc3c2O)cc1

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 11/20 0.65
▸ PRMT1 Q99873 2/20 0.58
▸ PRMT3 O60678 1/20 0.58
▸ EP300 Q09472 1/20 0.58
▸ PRMT6 Q96LA8 1/20 0.58
▸ PHLPP2 Q6ZVD8 3/20 0.56
▸ CD40 P25942 1/20 0.52
▸ CD40LG P29965 1/20 0.52
▸ CARM1 Q86X55 1/20 0.49
▸ ALDH1A1 P00352 1/20 0.45
▸ CYP1A2 P05177 1/20 0.45
▸ HIF1A Q16665 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17515772 0.93 ENPP2 (0.65) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL17518422 0.91 ENPP2 (0.70) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL17518419 0.90 ENPP2 (0.67) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL17540349 0.90 ENPP2 (0.79) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL17545735 0.90 ENPP2 (0.73) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL2615790 0.90 ENPP2 (0.71) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL19235037 0.90 ENPP2 (0.73) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL17540346 0.89 ENPP2 (0.79) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL17540345 0.89 ENPP2 (0.79) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL19235035 0.89 ENPP2 (0.67) ENPP2PRMT1PRMT3EP300PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170153361-A1 Achromatic Polarizing Plate With High-Transmissivity And High-Degree Of Polarization NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-06-01 — — US disclosed
US-20160041321-A1 Achromatic Dye-Based Highly-Transmissive Polarization Element, And Polarization Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-02-11 — — US disclosed
US-20160041322-A1 Achromatic Polarization Element, And Polarization Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-02-11 — — US disclosed
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