⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3310419 | 0.73 | CA2 (0.41) | — | |
| SCHEMBL2704257 | 0.73 | — | — | |
| SCHEMBL4422753 | 0.73 | TDP1 (0.39) | — | |
| SCHEMBL1819326 | 0.71 | — | — | |
| SCHEMBL8805581 | 0.71 | — | — | |
| SCHEMBL208791 | 0.71 | — | — | |
| SCHEMBL177789 | 0.71 | — | — | |
| SCHEMBL2059944 | 0.71 | CA1 (0.44) | — | |
| SCHEMBL161898 | 0.71 | — | — | |
| SCHEMBL19630917 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118576-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | IMMUNIC AG (DE) | 2023-06-29 | — | — | WO | disclosed |
| EP-3825312-A1 | INTERMEDIATES FOR PREPARING INHIBITORS OF HEPATITIS C VIRUS | Gilead Pharmasset LLC (US) | 2021-05-26 | — | — | EP | disclosed |
| EP-2863916-B1 | SUBSTITUTED PYRIDINE SPLEEN TYROSINE KINASE (SYK) INHIBITORS | MERCK SHARP & DOHME (US) | 2018-07-18 | — | — | EP | disclosed |
| CN-107629057-A | BET protein inhibitors and its application | 上海勋和医药科技有限公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-104045644-B | The manufacture method and metal phthalocyanine compound of metal phthalocyanine compound | 富士胶片株式会社 | 2018-01-16 | — | — | CN | disclosed |
| US-20170333399-A1 | Isoxazole Derivatives as FXR Agonists and Methods of Use Thereof | ENANTA PHARMACEUTICALS, INC. | 2017-11-23 | — | — | US | disclosed |
| US-20170334894-A1 | Isoxazole Derivatives as FXR Agonists and Methods of Use Thereof | ENANTA PHARMACEUTICALS, INC. | 2017-11-23 | — | — | US | disclosed |
| US-20170313745-A1 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD SCIENCES, INC. | 2017-11-02 | — | — | US | disclosed |
| US-20170290827-A1 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD PHARMASSET LLC | 2017-10-12 | — | — | US | disclosed |
| WO-2017156165-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
| EP-0766669-A1 | TRI-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1997-04-09 | — | — | EP | disclosed |
| EP-0766671-A1 | TETRA-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1997-04-09 | — | — | EP | disclosed |
| WO-1996008577-A1 | BIOCONVERSION PROCESS FOR THE SYNTHESIS OF TRANS-HYDROXY SULFONE | MERCK & CO., INC. (US) | 1996-03-21 | — | — | WO | disclosed |
| WO-1996000215-A1 | SUBSTITUTED OXIME DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1996-01-04 | — | — | WO | disclosed |
| WO-1995035281-A1 | TRI-SUBSTITUTED PHENYL DERIVATES USEFUL AS PDE IV INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1995-12-28 | — | — | WO | disclosed |
| WO-1995035283-A1 | TRI-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1995-12-28 | — | — | WO | disclosed |
| WO-1995035285-A1 | TETRA-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1995-12-28 | — | — | WO | disclosed |
| US-5474919-A | Bioconversion process for the synthesis of transhydroxy sulfone by Rhodotorula rubra or Rhodotorula piliminae | MERCK & CO., INC. (US) | 1995-12-12 | — | — | US | disclosed |
| US-4414152-A | Bis aryl-azo derivatives of 2,3-naphthalenediol | EASTMAN KODAK COMPANY (US) | 1983-11-08 | — | — | US | disclosed |
| US-4414320-A | Bis aryl-azo derivatives of 2,3-naphthalenediol and electrophotographic liquid developer compositions containing them | EASTMAN KODAK COMPANY (US) | 1983-11-08 | — | — | US | disclosed |