Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16061067 | 0.81 | BTK (0.40) | DHODHL3MBTL1SIGMAR1KMT2APTGS2 | |
| SCHEMBL17486924 | 0.80 | MKNK1 (0.40) | MKNK1MKNK2P2RX7DHODHALDH1A1 | |
| SCHEMBL2108548 | 0.73 | MAPT (0.36) | DHODHALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL17517033 | 0.72 | BRD4 (0.41) | MKNK1MKNK2ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL2108531 | 0.70 | HCAR2 (0.36) | DHODHALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL2108726 | 0.69 | HCAR2 (0.38) | DHODHALDH1A1L3MBTL1 | |
| SCHEMBL3421959 | 0.69 | MKNK1 (0.52) | MKNK1MKNK2P2RX7L3MBTL1TDO2 | |
| SCHEMBL31469002 | 0.69 | MKNK1 (0.52) | MKNK1MKNK2P2RX7L3MBTL1TDO2 | |
| SCHEMBL28301632 | 0.68 | MKNK1 (0.58) | MKNK1MKNK2P2RX7DHODHPTGS2 | |
| SCHEMBL2109941 | 0.68 | WDR5 (0.36) | HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039801-A1 | SUBSTITUTED ALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | CYTOKINETICS, INC. (US) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039801-A1 | SUBSTITUTED ALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | HBB, MB, HBG2 | MKNK1 4351/4885MKNK2 4280/4885P2RX7 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.