Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 9/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | GRN | P28799 | 3/20 | 0.57 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | HTR1E | P28566 | 1/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145690 | 0.83 | NPSR1 (0.72) | NPSR1ALDH1A1L3MBTL1GRNSORT1 | |
| SCHEMBL1897745 | 0.82 | NPSR1 (0.71) | NPSR1ALDH1A1L3MBTL1GRNSORT1 | |
| SCHEMBL1898164 | 0.80 | NPSR1 (0.89) | NPSR1ALDH1A1L3MBTL1GRNSORT1 | |
| SCHEMBL148799 | 0.80 | NPSR1 (0.67) | NPSR1ALDH1A1L3MBTL1GRNSORT1 | |
| SCHEMBL144524 | 0.78 | NPSR1 (0.70) | NPSR1ALDH1A1L3MBTL1GRNSORT1 | |
| SCHEMBL1899459 | 0.77 | NPSR1 (1.00) | NPSR1ALDH1A1L3MBTL1GRNSORT1 | |
| SCHEMBL146787 | 0.76 | NPSR1 (0.74) | NPSR1ALDH1A1L3MBTL1GRNSORT1 | |
| SCHEMBL143529 | 0.76 | NPSR1 (0.67) | NPSR1ALDH1A1L3MBTL1GRNSORT1 | |
| SCHEMBL143851 | 0.76 | NPSR1 (0.81) | NPSR1ALDH1A1L3MBTL1GRNSORT1 | |
| SCHEMBL1899685 | 0.76 | NPSR1 (0.85) | NPSR1ALDH1A1L3MBTL1GRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059047-A1 | DIFFERENTIATION MODULATING AGENTS AND USES THEREFOR | VERVA PHARMACEUTICALS PTY LTD (AU) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059047-A1 | DIFFERENTIATION MODULATING AGENTS AND USES THEREFOR | FGF1, FABP4, FGF2 | NPSR1 3871/4885ALDH1A1 1103/4885L3MBTL1 1130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.