Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 15/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17520385 | 0.87 | DUT (0.35) | DUTALDH1A1TSHR | |
| SCHEMBL4790668 | 0.78 | CA1 (0.34) | ALDH1A1 | |
| SCHEMBL17520383 | 0.75 | EPHX1 (0.37) | — | |
| SCHEMBL20376222 | 0.74 | ALDH1A1 (0.33) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL13164464 | 0.73 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL21189211 | 0.71 | — | — | |
| SCHEMBL19558179 | 0.71 | DUT (0.34) | DUT | |
| SCHEMBL24522266 | 0.69 | TRPA1 (0.32) | — | |
| SCHEMBL9888776 | 0.68 | GAA (0.51) | GAAL3MBTL1ALDH1A1TSHRKDM4E | |
| SCHEMBL1754136 | 0.68 | PARG (0.37) | TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128720-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-07-12 | — | — | WO | disclosed |
| US-9809571-B2 | Deoxyuridine triphosphatase inhibitors | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-11-07 | — | — | US | disclosed |
| US-9790214-B2 | Heteroatom containing deoxyuridine triphosphatase inhibitors | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-10-17 | — | — | US | disclosed |
| US-20160326149-A1 | HETEROATOM CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2016-11-10 | — | — | US | disclosed |
| US-20160039788-A1 | DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326149-A1 | HETEROATOM CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | TYMP, DUT, TYMS | DUT 2/4885GAA 527/4885L3MBTL1 1184/4885 |
| US-20160039788-A1 | DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | DUT, TYMP, DPYD | DUT 1/4885GAA 346/4885L3MBTL1 1873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.