Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401163 | 0.86 | LMNA (0.70) | LMNAMAPTMEN1KMT2AGAA | |
| SCHEMBL28470333 | 0.84 | LMNA (0.74) | LMNAMAPTMEN1KMT2AGAA | |
| SCHEMBL8372051 | 0.83 | LMNA (0.69) | LMNAMAPTMEN1KMT2AGAA | |
| SCHEMBL17520529 | 0.80 | LMNA (0.62) | LMNAMAPTMEN1KMT2AGAA | |
| SCHEMBL13836644 | 0.79 | LMNA (0.64) | LMNAMAPTMEN1KMT2AGAA | |
| SCHEMBL28464367 | 0.78 | LMNA (0.62) | LMNAMAPTMEN1KMT2AGAA | |
| SCHEMBL11112953 | 0.78 | MEN1 (0.64) | LMNAMAPTMEN1KMT2AGAA | |
| SCHEMBL17520530 | 0.77 | LMNA (0.59) | LMNAMAPTMEN1KMT2AGAA | |
| SCHEMBL29630338 | 0.77 | LMNA (0.61) | LMNABCHEACHEPOLBABCG2 | |
| SCHEMBL29630294 | 0.77 | LMNA (0.61) | LMNAMAPTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020369-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | UNIVERSITÄT REGENSBURG (DE) | 2016-02-11 | — | — | WO | disclosed |