Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 11/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12831402 | 0.86 | HDAC1 (0.61) | LMNAMEN1KMT2AGAAMAPT | |
| SCHEMBL18688841 | 0.84 | KDM4E (0.75) | LMNAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL28465323 | 0.83 | LMNA (0.57) | LMNAMEN1KMT2AGAAMAPT | |
| SCHEMBL18689206 | 0.83 | LMNA (0.68) | LMNAMEN1KMT2AMAPTKIF11 | |
| SCHEMBL9401163 | 0.82 | LMNA (0.70) | LMNAMEN1KMT2AGAAMAPT | |
| SCHEMBL28470333 | 0.82 | LMNA (0.74) | LMNAMEN1KMT2AGAAMAPT | |
| SCHEMBL18688845 | 0.81 | KDM4E (0.74) | LMNAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL18688577 | 0.81 | ADRA2C (0.53) | LMNAMEN1KMT2AGAAMAPT | |
| SCHEMBL18688839 | 0.80 | KDM4E (0.73) | LMNAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL18689328 | 0.80 | KDM4E (0.73) | LMNAMEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459951-B1 | TETRAHYDRO-BETA-CARBOLINE ALKALOID DERIVATIVES, METHOD FOR PREPARING THE SAME AND USE IN ASPECTS OF PREVENTING AND TREATING PLANT VIRUSES, AS FUNGICIDES AND INSECTICIDES | JINGBO AGROCHEMICALS TECH CO LTD (CN) | 2022-05-11 | — | — | EP | claimed |
| EP-3459950-B1 | TETRAHYDRO-BETA-CARBOLINE ALKALOID DERIVATIVES, METHOD FOR PREPARING THE SAME AND USE IN ASPECTS OF PREVENTING AND TREATING PLANT VIRUSES, AS FUNGICIDES AND INSECTICIDES | JINGBO AGROCHEMICALS TECH CO LTD (CN) | 2022-05-18 | — | — | EP | disclosed |
| EP-3459951-B1 | TETRAHYDRO-BETA-CARBOLINE ALKALOID DERIVATIVES, METHOD FOR PREPARING THE SAME AND USE IN ASPECTS OF PREVENTING AND TREATING PLANT VIRUSES, AS FUNGICIDES AND INSECTICIDES | JINGBO AGROCHEMICALS TECH CO LTD (CN) | 2022-05-11 | — | — | EP | disclosed |