Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 14/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401163 | 0.82 | LMNA (0.70) | LMNAABCG2ABCB1ALDH1A1BCHE | |
| SCHEMBL28470333 | 0.82 | LMNA (0.74) | LMNAABCG2ABCB1BCHEACHE | |
| SCHEMBL8372051 | 0.79 | LMNA (0.69) | LMNAABCG2ABCB1BCHEACHE | |
| SCHEMBL17520528 | 0.77 | LMNA (0.73) | LMNAABCG2ABCB1BCHEACHE | |
| SCHEMBL9913669 | 0.76 | ABCG2 (0.72) | LMNAABCG2ABCB1ALDH1A1TP53 | |
| SCHEMBL28464367 | 0.76 | LMNA (0.62) | LMNAABCG2ABCB1ALDH1A1BCHE | |
| SCHEMBL17520529 | 0.76 | LMNA (0.62) | LMNAABCG2ABCB1ALDH1A1BCHE | |
| SCHEMBL11112953 | 0.76 | MEN1 (0.64) | LMNAABCG2ABCB1BCHEACHE | |
| SCHEMBL3712664 | 0.75 | ABCG2 (1.00) | LMNAABCG2ABCB1TP53 | |
| SCHEMBL29630294 | 0.75 | LMNA (0.61) | LMNAABCG2ABCB1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459951-B1 | TETRAHYDRO-BETA-CARBOLINE ALKALOID DERIVATIVES, METHOD FOR PREPARING THE SAME AND USE IN ASPECTS OF PREVENTING AND TREATING PLANT VIRUSES, AS FUNGICIDES AND INSECTICIDES | JINGBO AGROCHEMICALS TECH CO LTD (CN) | 2022-05-11 | — | — | EP | claimed |