Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085681 | 0.80 | HCAR2 (0.44) | MAPTHCAR2ATM | |
| SCHEMBL5611325 | 0.80 | HCAR2 (0.44) | MAPTHCAR2ATM | |
| SCHEMBL5611334 | 0.80 | HCAR2 (0.44) | MAPTHCAR2ATM | |
| SCHEMBL663907 | 0.79 | HCAR2 (0.52) | MAPTHCAR2ATM | |
| SCHEMBL663908 | 0.79 | HCAR2 (0.52) | MAPTHCAR2ATM | |
| SCHEMBL372677 | 0.77 | TDP1 (0.41) | MAPTHCAR2ATM | |
| Hydrochloric Acid SCHEMBL665362 | 0.77 | MAPT (0.50) | MAPTHCAR2ATM | |
| SCHEMBL13883741 | 0.77 | HDAC6 (0.33) | — | |
| SCHEMBL16860054 | 0.77 | HDAC6 (0.33) | — | |
| Hydrochloric Acid SCHEMBL665363 | 0.77 | MAPT (0.50) | MAPTHCAR2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160046634-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046634-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | PRKACA, PRKDC, AURKC | MAPT 4190/4885HCAR2 4178/4885ATM 511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.