SCHEMBL372677

SCHEMBL372677

CN(C)C=CC(=O)OCC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
KMT2A Q03164 2/20 0.35
MAPT P10636 4/20 0.33
ALDH1A1 P00352 4/20 0.33
HPGD P15428 2/20 0.33
RECQL P46063 2/20 0.32
HCAR2 Q8TDS4 2/20 0.32
ATM Q13315 1/20 0.32
RAB9A P51151 3/20 0.31
NPC1 O15118 2/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2C19 P33261 2/20 0.31
LMNA P02545 2/20 0.31
HTT P42858 1/20 0.31
ALOX12 P18054 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5611334 0.83 HCAR2 (0.44) KMT2AMAPTALDH1A1HCAR2ATM
SCHEMBL8085681 0.83 HCAR2 (0.44) KMT2AMAPTALDH1A1HCAR2ATM
SCHEMBL5611325 0.83 HCAR2 (0.44) KMT2AMAPTALDH1A1HCAR2ATM
SCHEMBL21126304 0.79 ATM (0.46) TDP1KMT2AMAPTALDH1A1HPGD
SCHEMBL17522209 0.77 MAPT (0.33) MAPTHCAR2ATM
SCHEMBL10943665 0.77 GSTP1 (0.38) KMT2AALDH1A1HCAR2ATMCYP2C19
SCHEMBL15794884 0.77 HCAR2 (0.35) KMT2AALDH1A1HCAR2ATMCYP2C19
SCHEMBL9004563 0.77 GSTP1 (0.38) KMT2AALDH1A1HCAR2ATMCYP2C19
SCHEMBL286141 0.77 HCAR2 (0.56) TDP1KMT2AMAPTALDH1A1HCAR2
SCHEMBL8354202 0.77 HCAR2 (0.56) TDP1KMT2AMAPTALDH1A1HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7914864-B2 self-adhesion latex comprising shell-core polymers used as substrate coatings; improved image quality HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2011-03-29 US claimed
EP-1842601-B1 Method for forming functional layers CIBA HOLDING INC (CH) 2009-07-22 EP claimed
US-7229736-B2 Liquid electrophotographic toners comprising amphipathic copolymers having acidic or basic functionality and wax having basic or acidic functionality SAMSUNG ELECTRONICS COMPANY (KR) 2007-06-12 US claimed
US-7202003-B2 Dry electrophotographic toners comprising amphipathic copolymers having basic functionality SAMSUNG ELECTRONICS COMPANY (KR) 2007-04-10 US claimed
US-20060246291-A1 Method for forming functional layers CIBA SPECIALTY CHEMICALS CORP. 2006-11-02 US claimed
US-20060093954-A1 Liquid electrophotographic toners comprising amphipathic copolymers having acidic or basic functionality and wax having basic or acidic functionality HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2006-05-04 US claimed
US-7018767-B2 Gel organosol including amphipathic copolymeric binder having acid/base functionality and liquid toners for electrophotographic applications SAMSUNG ELECTRONICS COMPANY (KR) 2006-03-28 US claimed
US-7014972-B2 Gel organosol including amphipathic copolymeric binder having hydrogen bonding functionality and liquid toners for electrophotographic applications SAMSUNG ELECTRONICS COMPANY (KR) 2006-03-21 US claimed
EP-1615081-A2 Dry electrophotographic toners comprising amphipathic copolymers having basic functionalitiy Samsung Electronics Co., Ltd. (KR) 2006-01-11 EP claimed
US-20060003246-A1 Dry electrophotographic toners comprising amphipathic copolymers having basic functionality S-PRINTING SOLUTION CO., LTD. (KR) 2006-01-05 US claimed
US-20050191445-A1 System and a method for forming a heat fusible microporous ink receptive coating HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2005-09-01 US claimed
US-20050095524-A1 Gel organosol including amphipathic copolymeric binder having hydrogen bonding functionality and liquid toners for electrophotographic applications S-PRINTING SOLUTION CO., LTD. (KR) 2005-05-05 US claimed
US-6849591-B1 Microcapsule preparations and detergents and cleaning agents containing microcapsules BASF AKTIENGESELLSCHAFT (DE) 2005-02-01 US claimed
EP-1494086-A1 Gel organosol including amphipathic copolymeric binder having acid/base functionality and liquid toners for electrophotographic applications Samsung Electronics Co., Ltd. (KR) 2005-01-05 EP claimed
EP-1494084-A2 Gel organosol including amphipathic copolymeric binder having hydrogen bonding functionality and liquid toners for electrophotographic application Samsung Electronics Co., Ltd. (KR) 2005-01-05 EP claimed
US-20040265722-A1 Gel organosol including amphipathic copolymeric binder having acid/base functionality and liquid toners for electrophotographic applications HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2004-12-30 US claimed
US-5266646-A Thickeners for waterbase paints; viscosity stabilizers to colorants; heat resistance; blister resistance; color float; syneresis resistance ROHM AND HAAS COMPANY (US) 1993-11-30 US claimed
US-12559584-B2 Aqueous dispersion opacifying pigment-binder hybrid polymer particles ROHM AND HAAS COMPANY (US) 2026-02-24 US disclosed
EP-0166009-A1 Photopolymerizable dental composition for preparing crowns and bridges DENTSPLY GMBH (DE) 1986-01-02 EP disclosed
EP-0126866-A1 Organic amine salt of an acid, manufacture and use as accelerator DENTSPLY INTERNATIONAL, INC. (US) 1984-12-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559584-B2 Aqueous dispersion opacifying pigment-binder hybrid polymer particles MPST, SULT1E1, SULT1A1 TDP1 2029/4885KMT2A 1109/4885MAPT 58/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.