Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 4/20 | 0.49 |
| ▸ | GABRD | O14764 | 4/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.49 |
| ▸ | GABRE | P78334 | 4/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.49 |
| ▸ | QPCT | Q16769 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | TYR | P14679 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12714390 | 0.70 | APP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28422580 | 0.68 | ABCB1 (0.74) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1985238 | 0.67 | MGAM (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9883329 | 0.66 | USP2 (0.77) | QPCTMEN1KMT2AUSP2POLB | |
| SCHEMBL20957619 | 0.66 | HSD17B3 (0.58) | CYP3A4MAPTALDH1A1HPGDESR2 | |
| SCHEMBL8477643 | 0.66 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2775968 | 0.66 | USP2 (0.63) | MEN1KMT2AUSP2POLBATM | |
| SCHEMBL26772564 | 0.65 | CLK2 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21648249 | 0.65 | MAP1LC3B (0.74) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Norartocarpetin SCHEMBL29435851 | 0.65 | BACE1 (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445702-B2 | Zinc binding compounds and their method of use | Life Technologies Corporation (US) | 2013-05-21 | — | — | US | disclosed |
| US-20110159517-A1 | Zinc binding compounds and their method of use | Life Technologies Corporation (US) | 2011-06-30 | — | — | US | disclosed |
| US-20090181364-A1 | ZINC BINDING COMPOUNDS AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2009-07-16 | — | — | US | disclosed |
| US-20050250214-A1 | Zinc binding compounds and their method of use | MOLECULAR PROBES, INC. | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110159517-A1 | Zinc binding compounds and their method of use | SLC30A6, SLC30A7, SLC39A11 | GABRP 536/4885GABRD 1178/4885GABRA1 540/4885 |
| US-20050250214-A1 | Zinc binding compounds and their method of use | SLC30A6, SLC30A7, SLC39A11 | GABRP 532/4885GABRD 1221/4885GABRA1 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.