Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 6/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LIG1 | P18858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17523302 | 1.00 | OPRM1 (0.40) | OPRM1SLC6A9KDM1ARCOR1HSD11B1 | |
| SCHEMBL17523288 | 0.90 | KDM1A (0.42) | SLC6A9KDM1AHSD11B1ALDH1A1MAPT | |
| SCHEMBL17523290 | 0.90 | KDM1A (0.42) | SLC6A9KDM1AHSD11B1ALDH1A1MAPT | |
| SCHEMBL17523292 | 0.87 | SLC6A9 (0.40) | OPRM1SLC6A9KDM1AALDH1A1MAOA | |
| SCHEMBL17523291 | 0.87 | SLC6A9 (0.40) | OPRM1SLC6A9KDM1AALDH1A1MAOA | |
| SCHEMBL17523304 | 0.86 | CYP2C9 (0.44) | KDM1ARCOR1HSD11B1ALDH1A1KMT2A | |
| SCHEMBL17523295 | 0.86 | CYP2C9 (0.44) | KDM1ARCOR1HSD11B1ALDH1A1KMT2A | |
| SCHEMBL17523297 | 0.81 | SLC6A9 (0.40) | OPRM1SLC6A9KDM1AALDH1A1MAPT | |
| SCHEMBL17523298 | 0.81 | SLC6A9 (0.40) | OPRM1SLC6A9KDM1AALDH1A1MAPT | |
| SCHEMBL17523299 | 0.80 | KDM1A (0.46) | KDM1ARCOR1HSD11B1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039827-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039827-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | CBR1, CBR3, CAT | OPRM1 1153/4885SLC6A9 2425/4885KDM1A 3183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.