Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 8/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898379 | 1.00 | ALDH1A1 (0.53) | ALDH1A1FFAR1CPT2TDP1FDPS | |
| SCHEMBL10192067 | 0.97 | ALDH1A1 (0.56) | ALDH1A1FFAR1CPT2TDP1 | |
| SCHEMBL7602370 | 0.90 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL2945318 | 0.90 | ALDH1A1 (0.64) | ALDH1A1FFAR1CPT2TDP1FDPS | |
| SCHEMBL5915749 | 0.90 | ALDH1A1 (0.64) | ALDH1A1FFAR1CPT2TDP1FDPS | |
| SCHEMBL3040312 | 0.90 | ALDH1A1 (0.64) | ALDH1A1FFAR1CPT2TDP1FDPS | |
| SCHEMBL2943010 | 0.90 | ALDH1A1 (0.64) | ALDH1A1FFAR1CPT2TDP1FDPS | |
| SCHEMBL1269985 | 0.87 | ALDH1A1 (0.69) | ALDH1A1FFAR1CPT2TDP1FDPS | |
| SCHEMBL20509901 | 0.83 | TDP1 (0.36) | ALDH1A1FFAR1CPT2TDP1ACLY | |
| SCHEMBL20526404 | 0.83 | TDP1 (0.36) | ALDH1A1FFAR1CPT2TDP1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | ALDH1A1 2376/4885FFAR1 2686/4885CPT2 848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.