Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.33 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.30 |
| ▸ | PRKCG | P05129 | 2/20 | 0.30 |
| ▸ | PRKCB | P05771 | 2/20 | 0.30 |
| ▸ | PRKCA | P17252 | 2/20 | 0.30 |
| ▸ | PRKCH | P24723 | 2/20 | 0.30 |
| ▸ | PRKCI | P41743 | 2/20 | 0.30 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17524006 | 1.00 | CA2 (0.39) | CA2CA1MAPK1LPAR6LPAR1 | |
| SCHEMBL17524074 | 0.94 | ZDHHC7 (0.36) | CA2CA1LPAR6LPAR1LPAR4 | |
| SCHEMBL17524075 | 0.94 | ZDHHC7 (0.36) | CA2CA1LPAR6LPAR1LPAR4 | |
| SCHEMBL17524150 | 0.92 | ZDHHC7 (0.39) | CA2LPAR6LPAR1LPAR4LPAR5 | |
| SCHEMBL17524149 | 0.92 | ZDHHC7 (0.39) | CA2LPAR6LPAR1LPAR4LPAR5 | |
| SCHEMBL807201 | 0.83 | DNM1 (0.41) | CA2CA1LPAR6LPAR1LPAR4 | |
| SCHEMBL1659777 | 0.83 | — | — | |
| SCHEMBL17524009 | 0.83 | — | — | |
| SCHEMBL17524010 | 0.83 | — | — | |
| SCHEMBL17524078 | 0.81 | CYP4F2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | CA2 1053/4885CA1 4107/4885MAPK1 1050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.