Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17524030 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CA2TDP1LMNACYP3A4 | |
| SCHEMBL17524100 | 0.94 | ALDH1A1 (0.40) | ALDH1A1CA2TDP1LMNACYP3A4 | |
| SCHEMBL17524099 | 0.94 | ALDH1A1 (0.40) | ALDH1A1CA2TDP1LMNACYP3A4 | |
| SCHEMBL17524176 | 0.92 | LMNA (0.39) | ALDH1A1CA2TDP1LMNATSHR | |
| SCHEMBL17524175 | 0.92 | LMNA (0.39) | ALDH1A1CA2TDP1LMNATSHR | |
| SCHEMBL17523807 | 0.84 | LMNA (0.43) | ALDH1A1LMNARIPK1 | |
| SCHEMBL17523806 | 0.84 | LMNA (0.43) | ALDH1A1LMNARIPK1 | |
| SCHEMBL9173076 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CA2TDP1LMNACYP3A4 | |
| SCHEMBL16104742 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CA2TDP1LMNACYP3A4 | |
| SCHEMBL4887912 | 0.82 | ALDH1A1 (0.38) | ALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | ALDH1A1 2376/4885CA2 1053/4885TDP1 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.