SCHEMBL175241

SCHEMBL175241

C=CCN(CC=C)c1ccccn1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 4/20 0.44
ADRA2A P08913 4/20 0.44
DRD1 P21728 4/20 0.44
SLC6A4 P31645 4/20 0.44
SLC6A3 Q01959 4/20 0.44
KCNH2 Q12809 4/20 0.44
SLC6A2 P23975 3/20 0.44
HTR2A P28223 3/20 0.44
HRH1 P35367 3/20 0.44
ADRA1A P35348 2/20 0.44
ADRA2B P18089 2/20 0.44
ADRA2C P18825 1/20 0.44
OPRK1 P41145 1/20 0.44
CYP2D6 P10635 6/20 0.43
CYP2C19 P33261 3/20 0.43
KDM4E B2RXH2 5/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
LMNA P02545 2/20 0.42
MAPK1 P28482 1/20 0.42
CYP1A2 P05177 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13740973 0.84 CYP2D6 (0.52) CHRM2ADRA2ADRD1SLC6A4SLC6A3
SCHEMBL9248220 0.84 TSHR (0.41) CHRM2ADRA2ADRD1SLC6A4SLC6A3
SCHEMBL9278864 0.82 CYP2D6 (0.42) CHRM2ADRA2ADRD1SLC6A4SLC6A3
SCHEMBL9300866 0.81 CYP2D6 (0.41) CHRM2ADRA2ADRD1SLC6A4SLC6A3
SCHEMBL31497259 0.81 CYP2D6 (0.49) CHRM2ADRA2ADRD1SLC6A4SLC6A3
SCHEMBL9302381 0.81 CYP2D6 (0.41) CHRM2ADRA2ADRD1SLC6A4SLC6A3
SCHEMBL4070519 0.81 CYP2D6 (0.49) CHRM2ADRA2ADRD1SLC6A4SLC6A3
SCHEMBL6395273 0.81 CYP2D6 (0.41) CHRM2ADRA2ADRD1SLC6A4SLC6A3
SCHEMBL10619140 0.79 CYP2D6 (0.47) CHRM2ADRA2ADRD1SLC6A4SLC6A3
SCHEMBL6669910 0.77 CYP2D6 (0.38) CHRM2ADRA2ADRD1SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210403620-A1 FUNCTIONALIZED POLY(2,6-DIMETHYL PHENYLENE OXIDE) OLIGOMERS CONTAINING DICYCLOPENTADIENE, METHOD OF PRODUCING THE SAME AND USE THEREOF CPC CORP TAIWAN (TW) 2021-12-30 US claimed
US-11208406-B2 Disubstituted diaryloxybenzoheterodiazole compounds ENI S.P.A. (IT) 2021-12-28 US claimed
US-11183645-B2 Organic thin film and method for manufacturing organic thin film, organic electroluminescence element, display device, illumination device, organic thin film solar cell, thin film transistor, and coating composition NIPPON HOSO KYOKAI (JP) 2021-11-23 US claimed
CN-109970519-B Functionalized poly (2, 6-dimethylphenylene ether) oligomers containing dicyclopentadiene, process for their production and their use 台湾中油股份有限公司 2021-11-16 CN claimed
EP-2998285-B1 EXTRACTION OF CARBOXYLIC ACIDS FROM A DILUTE AQUEOUS STREAM PURAC BIOCHEM BV (NL) 2021-09-15 EP claimed
CN-108473486-B Disubstituted diaryloxybenzoheterodiazole compounds 埃尼股份公司 2021-06-01 CN claimed
CN-107710443-B Organic thin film, method for producing organic thin film, organic electroluminescent element, display device, lighting device, organic thin film solar cell, thin film transistor, and coating composition 日本放送协会 2019-12-17 CN claimed
EP-3568428-A1 DELAYED CURING CATALYSTS FOR THIOL/EPOXY REACTIONS PRC-Desoto International, Inc. (US) 2019-11-20 EP claimed
EP-3374357-B1 DISUBSTITUTED DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS ENI SPA (IT) 2019-10-02 EP claimed
CN-109970519-A Functionalized poly (2,6- dimethyl phenylate) oligomer, its manufacturing method containing dicyclopentadiene and application thereof 台湾中油股份有限公司 2019-07-05 CN claimed
US-4808731-A CONTACTING SUBSTITUTED PHTHALIC ANHYDRIDE WITH DIALKYLAMINOPYRIDINE IN REFLUXING NONPOLAR SOLVENT GENERAL ELECTRIC COMPANY (US) 1989-02-28 US claimed
US-4804773-A Production of gem-disubstituted cyclohexadienones ETHYL CORPORATION (US) 1989-02-14 US claimed
EP-0287340-A2 Novel acylation process for the synthesis of HMG-COA reductase inhibitors MERCK & CO. INC. (US) 1988-10-19 EP claimed
EP-0147879-B1 PROCESS FOR THE PREPARATION OF A HYDROXYLAMINE AKZO N.V. (NL) 1987-12-16 EP claimed
EP-0121112-B1 2'-DEOXY-3-PHOSPHONYLMETHYL NUCLEOSIDES AND METHOD FOR THEIR PREPARATION Gesellschaft für Biotechnologische Forschung mbH (GBF) (DE) 1987-05-13 EP claimed
EP-0218111-A1 Process for the preparation of tetrafluorobenzoic acid WARNER-LAMBERT COMPANY (US) 1987-04-15 EP claimed
EP-0147879-A1 Process for the preparation of a hydroxylamine AKZO N.V. (NL) 1985-07-10 EP claimed
EP-0140207-A2 A process for rapidly curing a brominated fluoroelastomer E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-05-08 EP claimed
EP-0014103-B1 IMPROVED PROCESS FOR THE MANUFACTURE OF CARBAMATES THE HALCON SD GROUP, INC. (US) 1983-05-11 EP claimed
US-4339616-A AMINE SALTS AS CATALYSTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1982-07-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11208406-B2 Disubstituted diaryloxybenzoheterodiazole compounds NR2E3, SCLY, NR2C2 CHRM2 622/4885ADRA2A 3460/4885DRD1 431/4885
US-20210403620-A1 FUNCTIONALIZED POLY(2,6-DIMETHYL PHENYLENE OXIDE) OLIGOMERS CONTAINING DICYCLOPENTADIENE, METHOD OF PRODUCING THE SAME AND USE THEREOF PUF60, PARG, PARP2 CHRM2 2478/4885ADRA2A 3902/4885DRD1 1587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.