Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | DRD1 | P21728 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31497259 | 1.00 | CYP2D6 (0.49) | CYP2D6CYP2C19PPARGPPARACHRM2 | |
| SCHEMBL1632588 | 0.81 | CYP2D6 (0.49) | CYP2D6CYP2C19PPARGPPARACHRM2 | |
| SCHEMBL28364297 | 0.81 | CYP2D6 (0.49) | CYP2D6CYP2C19PPARGPPARACHRM2 | |
| SCHEMBL13740973 | 0.81 | CYP2D6 (0.52) | CYP2D6CYP2C19CHRM2ADRA2ADRD1 | |
| SCHEMBL175241 | 0.81 | CHRM2 (0.44) | CYP2D6CYP2C19CHRM2ADRA2ADRD1 | |
| SCHEMBL9278864 | 0.79 | CYP2D6 (0.42) | CYP2D6CYP2C19CHRM2ADRA2ADRD1 | |
| SCHEMBL2101892 | 0.79 | CYP2D6 (0.53) | CYP2D6CYP2C19CHRM2ADRA2ADRD1 | |
| SCHEMBL14415503 | 0.78 | CDK1 (0.37) | CYP2D6CYP2C19SLC6A2KDM4ETSHR | |
| SCHEMBL9300866 | 0.78 | CYP2D6 (0.41) | CYP2D6CYP2C19PPARGPPARACHRM2 | |
| SCHEMBL9302381 | 0.78 | CYP2D6 (0.41) | CYP2D6CYP2C19CHRM2ADRA2ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082588-A1 | Process for producing fluorinated carbamates and isocyanates | REPSOL YPF, S.A. (ES) | 2009-03-26 | — | — | US | disclosed |
| EP-2036884-A1 | Process for producing fluorinated isocyanates and carbamates | REPSOL YPF S.A. (ES) | 2009-03-18 | — | — | EP | disclosed |
| US-7271172-B2 | Pyrrolidine and azetidine compounds as CCR5 antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-18 | — | — | US | disclosed |
| EP-0517542-B1 | Organic electroluminescence devices | SUMITOMO CHEMICAL CO (JP) | 1995-08-30 | — | — | EP | disclosed |
| EP-0517542-A1 | Organic electroluminescence devices | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082588-A1 | Process for producing fluorinated carbamates and isocyanates | SRM, CA4, PRMT3 | CYP2D6 3293/4885CYP2C19 921/4885PPARG 3479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.