Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17518372 | 0.80 | MAPT (0.34) | MAPTCACNA1BAPBA1CYP3A4CYP2C9 | |
| SCHEMBL10280918 | 0.75 | GRIK1 (0.34) | — | |
| SCHEMBL2038104 | 0.75 | MAPT (0.47) | MAPTCACNA1BAPBA1CYP3A4CYP2C9 | |
| SCHEMBL2038105 | 0.75 | MAPT (0.47) | MAPTCACNA1BAPBA1CYP3A4CYP2C9 | |
| SCHEMBL17919993 | 0.72 | GRIK1 (0.30) | — | |
| SCHEMBL17920241 | 0.72 | GRIK1 (0.30) | — | |
| SCHEMBL17518330 | 0.72 | — | — | |
| SCHEMBL17518252 | 0.67 | HCAR2 (0.38) | — | |
| SCHEMBL21989095 | 0.67 | TDP1 (0.41) | MAPTCACNA1BAPBA1CYP3A4CYP2C9 | |
| SCHEMBL17524626 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9266927-B2 | Cyclosporin A analogs | ALLERGAN, INC. (US) | 2016-02-23 | — | — | US | disclosed |