Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17518373 | 0.83 | — | — | |
| SCHEMBL17524671 | 0.80 | MAPT (0.42) | MAPTCACNA1BAPBA1CYP3A4CYP2C9 | |
| SCHEMBL17524673 | 0.78 | — | — | |
| SCHEMBL17920241 | 0.69 | GRIK1 (0.30) | — | |
| SCHEMBL17919993 | 0.69 | GRIK1 (0.30) | — | |
| SCHEMBL2038104 | 0.67 | MAPT (0.47) | MAPTCACNA1BAPBA1CYP3A4CYP2C9 | |
| SCHEMBL2038105 | 0.67 | MAPT (0.47) | MAPTCACNA1BAPBA1CYP3A4CYP2C9 | |
| SCHEMBL17920196 | 0.63 | — | — | |
| SCHEMBL15537387 | 0.63 | MAPT (0.33) | MAPTCACNA1BAPBA1CYP3A4CYP2C9 | |
| SCHEMBL17920200 | 0.60 | CTSK (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039880-A1 | CYCLOSPORIN A ANALOGS | ALLERGAN, INC. | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039880-A1 | CYCLOSPORIN A ANALOGS | TSLP, CHP1, PPP3R1 | MAPT 3620/4885CACNA1B 2947/4885APBA1 1315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.