Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RBBP9 | O75884 | 4/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.40 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27980177 | 0.97 | ALDH1A1 (0.64) | ALDH1A1PLA2G7ADORA2AADORA1PLA2G4A | |
| Trifluoroacetic Acid SCHEMBL27990749 | 0.85 | ADORA2A (0.52) | ALDH1A1PLA2G7ADORA2AADORA1PLA2G4A | |
| SCHEMBL28027939 | 0.84 | ALDH1A1 (0.67) | ALDH1A1PLA2G7ADORA2AADORA1PLA2G4A | |
| SCHEMBL2170448 | 0.82 | — | — | |
| SCHEMBL121301 | 0.82 | — | — | |
| SCHEMBL2008703 | 0.81 | PLA2G7 (0.57) | ALDH1A1PLA2G7ADORA2AADORA1PLA2G4A | |
| SCHEMBL149729 | 0.80 | — | — | |
| SCHEMBL555458 | 0.80 | — | — | |
| SCHEMBL16716388 | 0.80 | — | — | |
| SCHEMBL825807 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114524829-B | Preparation method of imidazo [2,1-b ] thiazole derivative | 新疆大学 | 2024-04-02 | — | — | CN | claimed |
| CN-110024660-A | A kind of method and vernalization soil making vernalization soil using sawdust as raw material | 雷军 | 2019-07-19 | — | — | CN | claimed |
| CN-109761976-A | The condensed Azadecalin glucocorticoid receptor modulators of octahydro | 科赛普特治疗公司 | 2019-05-17 | — | — | CN | claimed |
| CN-106029066-B | Octahydro fused azadecalin glucocorticoid receptor modulators | 科赛普特治疗公司 | 2019-03-15 | — | — | CN | claimed |
| CN-104619328-B | The condensed quinoline alkane glucocorticoid receptor modulator of heteroaryl -one | 科赛普特治疗学股份有限公司 | 2018-10-02 | — | — | CN | claimed |
| CN-104961707-B | Substituted thiazole ketone secretory protease inhibitors and preparation method thereof | 中国人民解放军第二军医大学 | 2017-07-28 | — | — | CN | claimed |
| CN-105214614-B | Linear thiazole ketone coadsorbent and preparation method thereof | 陕西理工学院 | 2017-05-10 | — | — | CN | claimed |
| CN-106518848-A | Novel chromene diarylurea compounds, and preparation method and application thereof | 中国人民解放军军事医学科学院毒物药物研究所 | 2017-03-22 | — | — | CN | claimed |
| CN-106518767-A | Substituted benzopyrazole diarylurea compound, preparation method and medical application thereof | 中国人民解放军军事医学科学院毒物药物研究所 | 2017-03-22 | — | — | CN | claimed |
| CN-106518766-A | Novel diaryl urea compounds, and preparation method and medical applications thereof | 中国人民解放军军事医学科学院毒物药物研究所 | 2017-03-22 | — | — | CN | claimed |
| CN-1543455-B | 3-phenoxy-4-pyridazinol derivatives and herbicidal compositions containing the same | SANKYO AGRO CO LTD | 2012-07-11 | — | — | CN | claimed |
| CN-102015719-A | Pyrrolotriazine kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2011-04-13 | — | — | CN | claimed |
| CN-101802610-A | A high throughput test method for evaluation of biocides against anaerobic microorganisms | DOW GLOBAL TECHNOLOGIES INC | 2010-08-11 | — | — | CN | claimed |
| CN-101723941-A | “1,2,4” oxadiazole as a metabotropic glutamate receptor-5 modulator | ASTRAZENECA AB | 2010-06-09 | — | — | CN | claimed |
| CN-101687790-A | Heterocyclic compounds as positive modulators of metabotropic glutamate receptor 2(MGLU2 receptor) | ABBOTT GMBH & CO KG | 2010-03-31 | — | — | CN | claimed |
| CN-1894241-A | \"1, 2, 4\" oxadiazoles as modulators of metabotropic glutamate receptor-5 | ASTRAZENECA AB (SE) | 2007-01-10 | — | — | CN | claimed |
| CN-1051546-C | Novel 1,1-bis (heteroazolyl) alkane derivatives and their use as neuroprotective agents | ASTRA AB (SE) | 2000-04-19 | — | — | CN | claimed |
| CN-1150426-A | Novel 1,1-bis (heteroazolyl) alkane derivatives and their use as neuroprotective agents | ASTRA AB (SE) | 1997-05-21 | — | — | CN | claimed |
| EP-0765325-A1 | NOVEL 1,1-BIS(HETEROAZOLYL)ALKANE DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE AGENTS | Astra Aktiebolag (SE) | 1997-04-02 | — | — | EP | claimed |
| WO-1995033747-A1 | NOVEL 1,1-BIS(HETEROAZOLYL)ALKANE DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE AGENTS | ASTRA AKTIEBOLAG (SE) | 1995-12-14 | — | — | WO | claimed |