Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 6/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17526489 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TSHRDNM1LMNAMAPT | |
| SCHEMBL17526734 | 0.98 | ALDH1A1 (0.42) | ALDH1A1TSHRDNM1LMNAMAPT | |
| SCHEMBL17526513 | 0.98 | ALDH1A1 (0.42) | ALDH1A1TSHRDNM1LMNAMAPT | |
| SCHEMBL17526696 | 0.91 | ALDH1A1 (0.43) | ALDH1A1TSHRDNM1LMNAMAPT | |
| SCHEMBL17526596 | 0.91 | ALDH1A1 (0.43) | ALDH1A1TSHRDNM1LMNAMAPT | |
| SCHEMBL10067651 | 0.85 | DNM1 (0.52) | ALDH1A1TSHRDNM1LMNACA2 | |
| SCHEMBL17200120 | 0.85 | DNM1 (0.58) | ALDH1A1TSHRDNM1LMNACA2 | |
| SCHEMBL6846200 | 0.85 | ALDH1A1 (0.58) | ALDH1A1TSHRDNM1LMNAMAPT | |
| SCHEMBL7928729 | 0.84 | ALDH1A1 (0.52) | ALDH1A1TSHRLMNAMAPTCA2 | |
| Hydrochloric Acid SCHEMBL30707 | 0.83 | DNM1 (0.60) | ALDH1A1TSHRDNM1LMNACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | ALDH1A1 2376/4885TSHR 4131/4885DNM1 3016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.