Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 1.00 |
| ▸ | RORB | Q92753 | 3/20 | 1.00 |
| ▸ | NR1I2 | O75469 | 1/20 | 1.00 |
| ▸ | RORA | P35398 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175635 | 0.93 | RORC (0.86) | RORCRORBNR1I2RORA | |
| SCHEMBL175550 | 0.92 | RORC (0.86) | RORCRORBNR1I2RORA | |
| SCHEMBL175214 | 0.92 | RORC (0.85) | RORCRORBNR1I2RORA | |
| SCHEMBL175442 | 0.92 | RORC (1.00) | RORCRORBNR1I2RORA | |
| SCHEMBL175284 | 0.91 | RORC (0.84) | RORCRORBNR1I2RORA | |
| SCHEMBL175604 | 0.91 | RORC (0.83) | RORCRORBNR1I2RORA | |
| SCHEMBL174641 | 0.90 | RORC (1.00) | RORCRORBNR1I2 | |
| SCHEMBL175313 | 0.90 | RORC (0.81) | RORCRORBNR1I2RORA | |
| SCHEMBL175182 | 0.90 | RORC (0.81) | RORCRORBNR1I2RORA | |
| SCHEMBL175507 | 0.89 | RORC (1.00) | RORCRORBNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250090499-A1 | COMPOSITIONS AND METHODS FOR IMPROVING BONE HEALTH USING SELF-EMULSIFYING FORMULATIONS OF DIINDOLYLMETHANE | BIORESPONSE, L.L.C. | 2025-03-20 | — | — | US | disclosed |
| US-20220280479-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | BIORESPONSE, L.L.C. | 2022-09-08 | — | — | US | disclosed |
| US-11337961-B2 | Self-emulsifying formulations of DIM-related indoles | BIORESPONSE, L.L.C. (US) | 2022-05-24 | — | — | US | disclosed |
| CN-108473426-B | Cyclic amine derivative and medical use thereof | 东丽株式会社 | 2021-09-07 | — | — | CN | disclosed |
| US-20210046046-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | BIORESPONSE, L.L.C. | 2021-02-18 | — | — | US | disclosed |
| US-10881649-B2 | Therapeutic agent or preventive agent for alopecia areata | TORAY INDUSTRIES, INC. (JP) | 2021-01-05 | — | — | US | disclosed |
| US-10799479-B2 | Self-emulsifying formulations of DIM-related indoles | BIORESPONSE, L.L.C. (US) | 2020-10-13 | — | — | US | disclosed |
| US-20200215046-A1 | THERAPEUTIC AGENT OR PREVENTIVE AGENT FOR ALOPECIA AREATA | TORAY INDUSTRIES, INC. (JP) | 2020-07-09 | — | — | US | disclosed |
| EP-3409660-B1 | CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | TORAY INDUSTRIES (JP) | 2020-07-01 | — | — | EP | disclosed |
| EP-3659602-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR ALOPECIA AREATA | Toray Industries, Inc. (JP) | 2020-06-03 | — | — | EP | disclosed |
| US-10441569-B2 | Self-emulsifying formulations of DIM-related indoles | BIORESPONSE, L.L.C. (US) | 2019-10-15 | — | — | US | disclosed |
| US-10364222-B2 | Cyclic amine derivative and medical use thereof | TORAY INDUSTRIES, INC. (JP) | 2019-07-30 | — | — | US | disclosed |
| US-20180370916-A1 | CYCLIC AMINE DERIVATIVE AND MEDICAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2018-12-27 | — | — | US | disclosed |
| EP-3409660-A1 | CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | Toray Industries, Inc. (JP) | 2018-12-05 | — | — | EP | disclosed |
| US-20180280347-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | BIORESPONSE, L.L.C. (US) | 2018-10-04 | — | — | US | disclosed |
| US-20180161308-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | BIORESPONSE, L.L.C. (US) | 2018-06-14 | — | — | US | disclosed |
| EP-3280398-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | Bioresponse LLC (US) | 2018-02-14 | — | — | EP | disclosed |
| WO-2016164770-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | BIORESPONSE, L.L.C. (US) | 2016-10-13 | — | — | WO | disclosed |
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220280479-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | IDO1, IDO2, CYP8B1 | RORC 933/4885RORB 228/4885NR1I2 2345/4885 |
| US-20250090499-A1 | COMPOSITIONS AND METHODS FOR IMPROVING BONE HEALTH USING SELF-EMULSIFYING FORMULATIONS OF DIINDOLYLMETHANE | IDO1, AHR, IDO2 | RORC 1526/4885RORB 522/4885NR1I2 3038/4885 |
| US-20200215046-A1 | THERAPEUTIC AGENT OR PREVENTIVE AGENT FOR ALOPECIA AREATA | RORA, RORB, RORC | RORC 3/4885RORB 2/4885NR1I2 64/4885 |
| US-10441569-B2 | Self-emulsifying formulations of DIM-related indoles | IDO1, IDO2, CYP8B1 | RORC 933/4885RORB 228/4885NR1I2 2345/4885 |
| US-20180370916-A1 | CYCLIC AMINE DERIVATIVE AND MEDICAL USE THEREOF | RORC, RORB, HRH3 | RORC 1/4885RORB 2/4885NR1I2 113/4885 |
| US-20210046046-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | IDO1, IDO2, CYP8B1 | RORC 1131/4885RORB 221/4885NR1I2 1938/4885 |
| US-11337961-B2 | Self-emulsifying formulations of DIM-related indoles | IDO1, IDO2, CYP8B1 | RORC 1131/4885RORB 221/4885NR1I2 1938/4885 |
| US-10364222-B2 | Cyclic amine derivative and medical use thereof | RORC, RORB, HRH3 | RORC 1/4885RORB 2/4885NR1I2 113/4885 |
| US-10881649-B2 | Therapeutic agent or preventive agent for alopecia areata | RORA, RORB, RORC | RORC 3/4885RORB 2/4885NR1I2 64/4885 |
| US-10799479-B2 | Self-emulsifying formulations of DIM-related indoles | IDO1, IDO2, CYP8B1 | RORC 1131/4885RORB 221/4885NR1I2 1938/4885 |
| US-20180280347-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | IDO1, IDO2, CYP8B1 | RORC 1131/4885RORB 221/4885NR1I2 1938/4885 |
| US-20180161308-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | IDO1, IDO2, CYP8B1 | RORC 933/4885RORB 228/4885NR1I2 2345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.