Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162961 | 1.00 | ALDH1A1 (0.68) | ALDH1A1LMNASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL17526522 | 0.92 | LMNA (0.73) | ALDH1A1LMNASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL17526538 | 0.92 | LMNA (0.73) | ALDH1A1LMNASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL1101572 | 0.92 | LMNA (0.73) | ALDH1A1LMNASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL8161588 | 0.92 | LMNA (0.81) | ALDH1A1LMNASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL317382 | 0.92 | ALDH1A1 (0.79) | ALDH1A1LMNASMN1; SMN2TSHRTDP1 | |
| SCHEMBL20983224 | 0.90 | LMNA (0.86) | ALDH1A1LMNASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL22462340 | 0.90 | LMNA (0.86) | ALDH1A1LMNASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL22462336 | 0.90 | LMNA (0.86) | ALDH1A1LMNASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL22462342 | 0.90 | LMNA (0.86) | ALDH1A1LMNASMN1; SMN2TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | ALDH1A1 2376/4885LMNA 3497/4885SMN1; SMN2 649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.