Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | CRHBP | P24387 | 3/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28950933 | 0.87 | NPSR1 (0.48) | ALDH1A1CRHBPCRHR2ATML3MBTL1 | |
| SCHEMBL4373512 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CRHBPCRHR2ATML3MBTL1 | |
| SCHEMBL6825300 | 0.83 | ATM (0.42) | ALDH1A1CRHBPCRHR2ATML3MBTL1 | |
| SCHEMBL4737917 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CRHBPCRHR2ATML3MBTL1 | |
| SCHEMBL8925970 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CRHBPCRHR2ATML3MBTL1 | |
| SCHEMBL30940203 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CRHBPCRHR2ATML3MBTL1 | |
| SCHEMBL5143722 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CRHBPCRHR2ATML3MBTL1 | |
| SCHEMBL5143721 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CRHBPCRHR2ATML3MBTL1 | |
| SCHEMBL16236160 | 0.80 | ALDH1A1 (0.45) | ALDH1A1CRHBPCRHR2ATML3MBTL1 | |
| Indoline SCHEMBL15618312 | 0.79 | DRD2 (0.36) | ALDH1A1ATMKMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334102-A1 | BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2003-08-13 | — | — | EP | claimed |
| WO-2002040475-A1 | BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-05-23 | — | — | WO | claimed |
| WO-2000069878-A1 | UNIVERSAL SOLID SUPPORTS SUITABLE FOR THE SYNTHESIS OF NUCLEIC ACIDS | NGO NAM Q (US) | 2000-11-23 | — | — | WO | claimed |
| CN-1041923-C | Piperazine derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-02-03 | — | — | CN | claimed |
| US-5059002-A | N-nitrophenyl carbamyl compounds | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-10-22 | — | — | US | claimed |
| EP-0434379-A1 | Second harmonic generation with archiral, straight-chain carbamic acid derivatives | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-06-26 | — | — | EP | claimed |
| EP-4320073-A1 | BIOORTHOGONAL REACTION SUITABLE FOR CLICK/UNCLICK APPLICATIONS | Dana-Farber Cancer Institute, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| US-11597727-B2 | Inhibitors of integrin alpha 2 beta 1 and methods of use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-03-07 | — | — | US | disclosed |
| US-20210387986-A1 | INHIBITORS OF INTEGRIN ALPHA 2 BETA 1 AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-12-16 | — | — | US | disclosed |
| EP-3154997-B9 | AURISTATIN DERIVATIVES AND CONJUGATES THEREOF | NOVARTIS AG (CH) | 2021-04-14 | — | — | EP | disclosed |
| EP-3765005-A1 | INHIBITORS OF INTEGRIN ALPHA 2 BETA 1 AND METHODS OF USE | The Regents of the University of California (US) | 2021-01-20 | — | — | EP | disclosed |
| CN-112105350-A | Inhibitors of integrin alpha 2 beta 1 and methods of use | 加利福尼亚大学董事会 | 2020-12-18 | — | — | CN | disclosed |
| EP-3154997-B1 | AURISTATIN DERIVATIVES AND CONJUGATES THEREOF | NOVARTIS AG (CH) | 2020-02-19 | — | — | EP | disclosed |
| EP-0755269-A1 | CONTRAST AGENTS | NYCOMED SALUTAR, INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| EP-0749452-A1 | POLYMER-CONJUGATED MALONIC ACID DERIVATIVES AND THEIR USE AS MEDICAMENTS AND DIAGNOSTIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995028967-A1 | CONTRAST AGENTS | NYCOMED SALUTAR INC (US) | 1995-11-02 | — | — | WO | disclosed |
| WO-1995024437-A1 | POLYMER-CONJUGATED MALONIC ACID DERIVATIVES AND THEIR USE AS MEDICAMENTS AND DIAGNOSTIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-14 | — | — | WO | disclosed |
| US-5382637-A | Solid state chain extension polymerization between Lewis acid oligomers and deblocked Lewis bases | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1995-01-17 | — | — | US | disclosed |
| US-5059002-A | N-nitrophenyl carbamyl compounds | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-10-22 | — | — | US | disclosed |
| EP-0434379-A1 | Second harmonic generation with archiral, straight-chain carbamic acid derivatives | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11597727-B2 | Inhibitors of integrin alpha 2 beta 1 and methods of use | ITGB1, ITGB2, ITGA2 | ALDH1A1 382/4885CRHBP 4557/4885CRHR2 4097/4885 |
| US-20210387986-A1 | INHIBITORS OF INTEGRIN ALPHA 2 BETA 1 AND METHODS OF USE | ITGB1, ITGB2, ITGA2 | ALDH1A1 382/4885CRHBP 4557/4885CRHR2 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.