Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | DRD4 | P21917 | 5/20 | 0.36 |
| ▸ | DRD3 | P35462 | 5/20 | 0.36 |
| ▸ | DRD1 | P21728 | 3/20 | 0.36 |
| ▸ | DRD5 | P21918 | 3/20 | 0.36 |
| ▸ | SLC10A2 | Q12908 | 10/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169922 | 0.81 | SLC10A2 (0.49) | SLC10A2 | |
| SCHEMBL17528460 | 0.81 | SLC10A2 (0.49) | SLC10A2 | |
| SCHEMBL9980442 | 0.80 | TRPM5 (0.35) | SLC10A2MEN1KMT2A | |
| SCHEMBL19179847 | 0.78 | SLC10A2 (0.54) | SLC10A2 | |
| SCHEMBL20169919 | 0.73 | DRD2 (0.34) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL17528453 | 0.73 | DRD2 (0.34) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL18748574 | 0.69 | SLC10A2 (0.58) | SLC10A2 | |
| SCHEMBL19170512 | 0.69 | SLC10A2 (0.58) | SLC10A2 | |
| SCHEMBL2591682 | 0.67 | SLC10A2 (0.82) | SLC10A2 | |
| SCHEMBL2591649 | 0.67 | SLC10A2 (0.82) | SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020785-A1 | SYNTHESIS OF BENZOTHIAZEPINES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED (GB) | 2016-02-11 | — | — | WO | disclosed |