SCHEMBL17528628

SCHEMBL17528628

C=CC(=O)OCCCOc1ccc(-c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.48
TSHR P16473 3/20 0.48
HPGD P15428 2/20 0.48
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
HTT P42858 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
FFAR4 Q5NUL3 1/20 0.40
RARB P10826 4/20 0.39
PPARA Q07869 2/20 0.39
PTGES O14684 1/20 0.39
ALOX5 P09917 1/20 0.39
PPARG P37231 1/20 0.39
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
HRH2 P25021 1/20 0.37
HRH1 P35367 1/20 0.37
KCNH2 Q12809 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19601508 1.00 THRB (0.48) THRBTSHRHPGDMEN1KMT2A
SCHEMBL19601496 0.98 THRB (0.52) THRBTSHRHPGDMEN1KMT2A
SCHEMBL19229843 0.97 THRB (0.48) THRBTSHRHPGDMEN1KMT2A
SCHEMBL19229844 0.96 THRB (0.47) THRBTSHRHPGDMEN1KMT2A
SCHEMBL14195437 0.96 TSHR (0.51) THRBTSHRHPGDMEN1KMT2A
SCHEMBL20414484 0.96 TSHR (0.51) THRBTSHRHPGDMEN1KMT2A
SCHEMBL13854044 0.94 THRB (0.56) THRBTSHRHPGDMEN1KMT2A
SCHEMBL12619858 0.92 TSHR (0.50) THRBTSHRHPGDMEN1KMT2A
SCHEMBL19757195 0.92 THRB (0.55) THRBTSHRHPGDMEN1KMT2A
SCHEMBL26532006 0.90 THRB (0.52) THRBTSHRHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11754901-B2 Electrochromic device, wearable device, and method for driving electrochromic device RICOH COMPANY, LTD. (JP) 2023-09-12 US disclosed
EP-3712695-B1 ELECTROCHROMIC DEVICE, WEARABLE DEVICE, AND METHOD FOR DRIVING ELECTROCHROMIC DEVICE RICOH CO LTD (JP) 2022-02-23 EP disclosed
US-11209713-B2 Electrochromic element and electrochromic dimming element RICOH COMPANY, LTD. (JP) 2021-12-28 US disclosed
US-20210032531-A1 ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2021-02-04 US disclosed
US-20200301226-A1 ELECTROCHROMIC DEVICE, WEARABLE DEVICE, AND METHOD FOR DRIVING ELECTROCHROMIC DEVICE RICOH COMPANY, LTD. (JP) 2020-09-24 US disclosed
EP-3712695-A1 ELECTROCHROMIC DEVICE, WEARABLE DEVICE, AND METHOD FOR DRIVING ELECTROCHROMIC DEVICE Ricoh Company, Ltd. (JP) 2020-09-23 EP disclosed
US-20190285960-A1 ELECTROCHROMIC DEVICE, ELECTRONIC DIMMING EYEGLASSES, AUGMENTED REALITY EYEGLASSES, AND CAMERA RICOH COMPANY, LTD. (JP) 2019-09-19 US disclosed
US-20170329199-A1 ELECTROCHROMIC DEVICE RICOH COMPANY, LTD. (JP) 2017-11-16 US disclosed
US-20170329198-A1 ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2017-11-16 US disclosed
US-20170235203-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT RICOH COMPANY, LTD. (JP) 2017-08-17 US disclosed
US-20170235203-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT RICOH COMPANY, LTD. (JP) 2017-08-17 US disclosed
WO-2016021129-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT RICOH COMPANY, LTD. (JP) 2016-02-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210032531-A1 ELECTROCHROMIC ELEMENT TMEM109, DSG1, GPX1 THRB 4504/4885TSHR 2752/4885HPGD 3606/4885
US-20170235203-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT TET2, TET1, TET3 THRB 658/4885TSHR 1413/4885HPGD 1942/4885
US-11209713-B2 Electrochromic element and electrochromic dimming element TET2, TET1, TET3 THRB 658/4885TSHR 1413/4885HPGD 1942/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.