Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700745 | 0.84 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1MEN1CYP1A2PKM | |
| SCHEMBL29603298 | 0.84 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1MEN1CYP1A2PKM | |
| SCHEMBL7031097 | 0.82 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL27615202 | 0.79 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1EPAS1PIK3CDPIK3CA | |
| SCHEMBL9448525 | 0.79 | CCR2 (0.40) | L3MBTL1ALDH1A1EPAS1CCR2 | |
| SCHEMBL2291957 | 0.78 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1EPAS1PIK3CDPIK3CA | |
| SCHEMBL28008541 | 0.78 | ERN1 (0.40) | L3MBTL1ALDH1A1EPAS1PIK3CDPIK3CA | |
| SCHEMBL5638874 | 0.77 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL7396658 | 0.75 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1TSHRCYP2C19EPAS1 | |
| SCHEMBL28785805 | 0.75 | EPAS1 (0.37) | L3MBTL1EPAS1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2763968-B1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LTD (GB) | 2016-02-24 | — | — | EP | disclosed |