Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29603298 | 1.00 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1MEN1CYP1A2PKM | |
| SCHEMBL17529293 | 0.84 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1MEN1CYP1A2PKM | |
| SCHEMBL29008152 | 0.84 | TSHR (0.35) | ALDH1A1MEN1CYP1A2PKMTSHR | |
| SCHEMBL5638874 | 0.83 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL5880820 | 0.82 | CA2 (0.46) | L3MBTL1ALDH1A1MEN1CYP1A2PKM | |
| SCHEMBL30239389 | 0.82 | CA2 (0.46) | L3MBTL1ALDH1A1MEN1CYP1A2PKM | |
| SCHEMBL7396658 | 0.81 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1TSHRCYP2C19EPAS1 | |
| SCHEMBL27615202 | 0.81 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1EPAS1PIK3CDPIK3CA | |
| SCHEMBL9448525 | 0.81 | CCR2 (0.40) | L3MBTL1ALDH1A1EPAS1CCR2 | |
| SCHEMBL4541616 | 0.80 | TRPV4 (0.36) | ALDH1A1MEN1CYP1A2PKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385832-B | Preparation method of 2, 3-dimethyl 4-methylsulfonyl bromobenzene | 江苏七洲绿色科技研究院有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117110489-A | Method for measuring content of topramezone intermediate | 山东亿盛实业股份有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-115874202-A | Method for producing sulfonyl compounds by electrolytic oxidation of thio compounds | 华东理工大学 | 2023-03-31 | — | — | CN | claimed |
| CN-115385832-A | Preparation method of 2, 3-dimethyl 4-methylsulfonyl bromobenzene | 江苏七洲绿色科技研究院有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-112094211-B | Preparation method of topramezone intermediate | 江苏七洲绿色化工股份有限公司 | 2022-04-29 | — | — | CN | claimed |
| CN-112694425-B | Method for preparing topramezone intermediate by using supergravity reaction | 利民化学有限责任公司 | 2022-04-26 | — | — | CN | claimed |
| CN-112694425-A | Method for preparing topramezone intermediate by using supergravity reaction | 利民化学有限责任公司 | 2021-04-23 | — | — | CN | claimed |
| CN-112321466-A | Synthetic method of topramezone key intermediate | 华东师范大学 | 2021-02-05 | — | — | CN | claimed |
| CN-112094211-A | Preparation method of topramezone intermediate | 江苏七洲绿色化工股份有限公司 | 2020-12-18 | — | — | CN | claimed |
| CN-118359520-A | Preparation method of topramezone intermediate | 山东亿盛实业股份有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-115385832-B | Preparation method of 2, 3-dimethyl 4-methylsulfonyl bromobenzene | 江苏七洲绿色科技研究院有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-115385832-B | Preparation method of 2, 3-dimethyl 4-methylsulfonyl bromobenzene | 江苏七洲绿色科技研究院有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-115385832-B | Preparation method of 2, 3-dimethyl 4-methylsulfonyl bromobenzene | 江苏七洲绿色科技研究院有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-114797738-B | Improved tubular reactor, production equipment using the same, and method for producing sulfonyl compound using the same | 兰升生物科技集团股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| US-20030018200-A1 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2003-01-23 | — | — | US | disclosed |
| US-6469176-B1 | CROP PROTECTION COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | disclosed |
| EP-1129082-A1 | METHOD AND NOVEL INTERMEDIATE PRODUCTS FOR PRODUCING ISOXAZOLIN-3-YL-ACYLBENZENES | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-05 | — | — | EP | disclosed |
| EP-1077955-A1 | METHOD FOR PRODUCING ISOXAZOLINE-3-YL-ACYL BENZENE | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000029394-A1 | METHOD AND NOVEL INTERMEDIATE PRODUCTS FOR PRODUCING ISOXAZOLIN-3-YL-ACYLBENZENES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-25 | — | — | WO | disclosed |
| WO-1999058509-A1 | METHOD FOR PRODUCING ISOXAZOLINE-3-YL-ACYL BENZENE | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018200-A1 | Preparation of isoxazolin-3-ylacylbenzenes | CYP2F1, UQCRB, CYP1B1 | L3MBTL1 2147/4885ALDH1A1 352/4885MEN1 3550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.