SCHEMBL17529660

SCHEMBL17529660

CO[Si](Cc1ccc(CI)cc1)(OC)OC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL415828 0.88 ESR1 (0.39) ESR1
SCHEMBL17529722 0.82 APP (0.42)
SCHEMBL988626 0.79 AGXT (0.43) ESR1
SCHEMBL3099832 0.79 TP53 (0.40)
SCHEMBL17529874 0.78 ESR1 (0.30) ESR1
SCHEMBL926687 0.78 TAAR1 (0.36)
SCHEMBL15734527 0.77 TAAR1 (0.43)
SCHEMBL15444222 0.77 CA1 (0.34) ESR1
SCHEMBL3361270 0.77 ESR1 (0.32) ESR1
SCHEMBL17529742 0.77 TAAR1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2990113-B1 METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS MARUZEN PETROCHEM CO LTD (JP) 2020-03-25 EP disclosed
EP-2990112-B1 METHOD FOR MANUFACTURING CATALYST FOR SYNTHESIZING CYCLIC CARBONATE MARUZEN PETROCHEM CO LTD (JP) 2020-03-25 EP disclosed
US-10029241-B2 Method for producing catalyst for cyclic carbonate synthesis MARUZEN PETROCHEMICAL CO., LTD. (JP) 2018-07-24 US disclosed
US-10011621-B2 Method for producing silica gel-immobolized phosphonium salt catalysts MARUZEN PETROCHEMICAL CO., LTD. (JP) 2018-07-03 US disclosed
US-9834536-B2 Method for producing catalyst for cyclic carbonate synthesis NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2017-12-05 US disclosed
US-20160108071-A1 METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS MARUZEN PETROCHEMICAL CO., LTD. (JP) 2016-04-21 US disclosed
US-20160067695-A1 METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS MARUZEN PETROCHEMICAL CO., LTD. (JP) 2016-03-10 US disclosed
US-20160060242-A1 METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2016-03-03 US disclosed
EP-2990114-A1 METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS National Institute of Advanced Industrial Science and Technology (JP) 2016-03-02 EP disclosed
EP-2990113-A1 METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS Maruzen Petrochemical Co., Ltd. (JP) 2016-03-02 EP disclosed
EP-2990112-A1 METHOD FOR MANUFACTURING CATALYST FOR SYNTHESIZING CYCLIC CARBONATE Maruzen Petrochemical Co., Ltd. (JP) 2016-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160067695-A1 METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS CYCS, CA7, CA9 ESR1 1021/4885
US-10029241-B2 Method for producing catalyst for cyclic carbonate synthesis CYCS, CA7, CA9 ESR1 1021/4885
US-20160108071-A1 METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS EPHX2, CA4, CA9 ESR1 2297/4885
US-20160060242-A1 METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS CA2, PLCB3, PHOSPHO1 ESR1 2871/4885
US-10011621-B2 Method for producing silica gel-immobolized phosphonium salt catalysts SIK2, SIK3, SIK1 ESR1 3389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.