Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.62 |
| ▸ | CTSL | P07711 | 6/20 | 0.57 |
| ▸ | CTSB | P07858 | 3/20 | 0.57 |
| ▸ | CTSK | P43235 | 3/20 | 0.57 |
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530248 | 0.91 | CTSL (0.59) | CTSSCTSLCTSBCTSKCCR1 | |
| SCHEMBL17530369 | 0.89 | CTSL (0.59) | CTSSCTSLCTSBCTSK | |
| SCHEMBL17529983 | 0.89 | CTSS (0.57) | CTSSCTSLCTSBCTSKCCR1 | |
| SCHEMBL17529971 | 0.89 | CTSS (0.56) | CTSSCTSLCTSBCTSK | |
| SCHEMBL17530169 | 0.88 | CTSS (0.56) | CTSSCTSLCTSBCTSKCCR1 | |
| SCHEMBL17530252 | 0.88 | CTSS (0.53) | CTSSCTSLCTSBCTSK | |
| SCHEMBL17530172 | 0.87 | CCR1 (0.52) | CTSSCTSLCTSBCTSKCCR1 | |
| SCHEMBL17530370 | 0.87 | CTSS (0.57) | CTSSCTSLCTSBCTSKGAA | |
| SCHEMBL17530392 | 0.85 | CTSL (0.53) | CTSSCTSLCTSBCTSK | |
| SCHEMBL17530007 | 0.85 | CTSL (0.62) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027284-A2 | PIPERIDINE UREAS AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS | ALKEM LABORATORIES LTD. (IN) | 2016-02-25 | — | — | WO | disclosed |