Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.56 |
| ▸ | CTSL | P07711 | 8/20 | 0.54 |
| ▸ | CTSK | P43235 | 5/20 | 0.54 |
| ▸ | CTSB | P07858 | 3/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530239 | 0.91 | CTSL (0.56) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17530013 | 0.90 | CTSL (0.56) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17530194 | 0.90 | CTSS (0.52) | CTSSCTSLCTSKCTSBHSD11B1 | |
| SCHEMBL17530227 | 0.89 | HSD11B1 (0.46) | CTSSCTSLCTSKCTSBHSD11B1 | |
| SCHEMBL17530170 | 0.89 | CTSS (0.51) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17529976 | 0.89 | CTSS (0.62) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17530199 | 0.88 | CTSS (0.48) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17530402 | 0.88 | CTSS (0.52) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17530189 | 0.86 | CTSS (0.46) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17529998 | 0.86 | CTSS (0.50) | CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027284-A2 | PIPERIDINE UREAS AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS | ALKEM LABORATORIES LTD. (IN) | 2016-02-25 | — | — | WO | disclosed |