Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 11/20 | 0.45 |
| ▸ | CTSK | P43235 | 5/20 | 0.45 |
| ▸ | CTSB | P07858 | 4/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.43 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.41 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.41 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.41 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.41 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.41 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.41 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.41 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.41 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530183 | 0.91 | CTSS (0.47) | CTSSCTSLCTSKCTSBPSMB5 | |
| SCHEMBL17529980 | 0.89 | CTSS (0.54) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17530393 | 0.88 | CTSL (0.46) | CTSSROCK2PRKG1CTSLCTSK | |
| SCHEMBL17530370 | 0.86 | CTSS (0.57) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17529983 | 0.86 | CTSS (0.57) | CTSSROCK2PRKG1CTSLCTSK | |
| SCHEMBL17530023 | 0.85 | CTSS (0.52) | CTSSROCK2PRKG1CTSLCTSK | |
| SCHEMBL17530026 | 0.84 | CTSS (0.52) | CTSSCTSLCTSKCTSBPOLB | |
| SCHEMBL17530252 | 0.84 | CTSS (0.53) | CTSSROCK2PRKG1CTSLCTSK | |
| SCHEMBL17530024 | 0.84 | CTSS (0.47) | CTSSROCK2PRKG1CTSLCTSK | |
| SCHEMBL17530237 | 0.83 | CTSS (0.52) | CTSSROCK2PRKG1CTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027284-A2 | PIPERIDINE UREAS AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS | ALKEM LABORATORIES LTD. (IN) | 2016-02-25 | — | — | WO | disclosed |