Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.52 |
| ▸ | CTSL | P07711 | 14/20 | 0.46 |
| ▸ | CTSK | P43235 | 6/20 | 0.42 |
| ▸ | CTSB | P07858 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17529981 | 0.91 | CTSS (0.48) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17530335 | 0.88 | CTSS (0.55) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17530252 | 0.87 | CTSS (0.53) | CTSSCTSLCTSKCTSBROCK2 | |
| SCHEMBL17530229 | 0.86 | CTSL (0.50) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17529983 | 0.86 | CTSS (0.57) | CTSSCTSLCTSKCTSBPOLB | |
| SCHEMBL17530369 | 0.85 | CTSL (0.59) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17530248 | 0.84 | CTSL (0.59) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17529977 | 0.83 | CTSS (0.52) | CTSSCTSLCTSKCTSBPOLB | |
| SCHEMBL17529970 | 0.82 | CCR1 (0.44) | CTSSCTSLCTSKCTSBROCK2 | |
| SCHEMBL17530026 | 0.82 | CTSS (0.52) | CTSSCTSLCTSKCTSBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027284-A2 | PIPERIDINE UREAS AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS | ALKEM LABORATORIES LTD. (IN) | 2016-02-25 | — | — | WO | disclosed |