Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 2/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | LCLAT1 | Q6UWP7 | 3/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20814652 | 0.85 | SERPINE1 (0.54) | SERPINE1PRMT6KMT2AMEN1POLB | |
| SCHEMBL1016073 | 0.83 | SERPINE1 (0.72) | SERPINE1PRMT6KMT2AMEN1POLB | |
| SCHEMBL17530198 | 0.77 | SERPINE1 (0.47) | SERPINE1PRMT6KMT2AMEN1POLB | |
| SCHEMBL1015063 | 0.75 | SERPINE1 (0.58) | SERPINE1PRMT6KMT2AMEN1POLB | |
| SCHEMBL1015171 | 0.71 | SERPINE1 (0.75) | SERPINE1PRMT6POLBPLA2G1BATG4B | |
| SCHEMBL10242930 | 0.69 | PRMT6 (0.60) | PRMT6KMT2AMEN1POLBKEAP1 | |
| SCHEMBL1318017 | 0.68 | WDR5 (0.53) | PRMT6POLBALDH1A1HPGDNPC1 | |
| SCHEMBL10243163 | 0.68 | PRMT6 (0.59) | PRMT6KMT2AMEN1POLBKEAP1 | |
| SCHEMBL1016234 | 0.67 | PRMT6 (0.58) | PRMT6KMT2AMEN1POLBKEAP1 | |
| SCHEMBL1317763 | 0.67 | TDP1 (0.59) | PRMT6KMT2AMEN1POLBKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2990057-A1 | NOVEL USE FOR PAI-1 INHIBITOR | Renascience Co., Ltd. (JP) | 2016-03-02 | — | — | EP | disclosed |